Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23558373 | 0.81 | GRIN2B (0.38) | ABL1SRCGRIN2B | |
| SCHEMBL29824826 | 0.81 | GAA (0.37) | ABL1SRCGRIN2B | |
| SCHEMBL23531654 | 0.81 | GAA (0.37) | ABL1SRCGRIN2B | |
| SCHEMBL23531684 | 0.80 | FPR2 (0.38) | ABL1CDK1SRCGRIN2BPRKCA | |
| SCHEMBL29824869 | 0.80 | FPR2 (0.38) | ABL1CDK1SRCGRIN2BPRKCA | |
| SCHEMBL29824911 | 0.79 | ABL1 (0.37) | ABL1SRCGRIN2B | |
| SCHEMBL23558170 | 0.79 | ABL1 (0.37) | ABL1SRCGRIN2B | |
| SCHEMBL23557919 | 0.78 | GRIN1 (0.36) | CDK1SRCRAPGEF4PDE4APDE4B | |
| SCHEMBL23558167 | 0.78 | GRIN2B (0.45) | GRIN2B | |
| SCHEMBL23558166 | 0.78 | TLR7 (0.43) | GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021123294-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2021-06-24 | — | — | WO | disclosed |