SCHEMBL23558678

SCHEMBL23558678

CCCCCOc1cc(N(c2ccccc2)c2ccccc2)c(-c2ccc(-c3ccccc3)c3oc4ccccc4c23)c2ccccc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25A P30304 1/20 0.41
CDC25B P30305 1/20 0.41
CDC25C P30307 1/20 0.41
THRA P10827 2/20 0.37
THRB P10828 2/20 0.37
KCNA3 P22001 1/20 0.36
LTB4R Q15722 5/20 0.35
LTB4R2 Q9NPC1 3/20 0.35
CDC14B O60729 1/20 0.34
CDC14A Q9UNH5 1/20 0.34
SOAT1 P35610 1/20 0.34
FAAH O00519 1/20 0.33
MGLL Q99685 1/20 0.33
HTT P42858 2/20 0.32
KMT2A Q03164 2/20 0.32
ADORA3 P0DMS8 1/20 0.32
LMNA P02545 1/20 0.32
POLB P06746 1/20 0.32
MAPT P10636 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23558680 0.85 CDC25A (0.42) CDC25ACDC25BCDC25CTHRATHRB
SCHEMBL23559095 0.72 GPR84 (0.34) CDC14BCDC14AKMT2AADORA3MAPT
SCHEMBL17917499 0.68 CDC14B (0.51) CDC25ACDC25BCDC25CCDC14BCDC14A
SCHEMBL22854798 0.68 CDC14B (0.51) CDC25ACDC25BCDC25CCDC14BCDC14A
SCHEMBL23027121 0.67 CDC14B (0.50) CDC14BCDC14AKMT2AADORA3LMNA
SCHEMBL22707251 0.67 CDC14B (0.50) CDC14BCDC14AKMT2AADORA3LMNA
SCHEMBL20462438 0.67 CDC14B (0.41) CDC14BCDC14AKMT2AADORA3MAPT
SCHEMBL24370006 0.67 CDC14B (0.45) CDC14BCDC14AKMT2AADORA3POLB
SCHEMBL25802412 0.67 CDC14B (0.42) CDC14BCDC14AKMT2AADORA3POLB
SCHEMBL19445001 0.67 CDC14B (0.43) CDC14BCDC14AKMT2AADORA3MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021121230-A1 COMPOUND, APPLICATION THEREOF, AND ORGANIC ELECTROLUMINESCENT DEVICE CONTAINING SAME 北京鼎材科技有限公司 2021-06-24 WO disclosed