Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.56 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | CKS1B | P61024 | 1/20 | 0.46 |
| ▸ | SKP1 | P63208 | 1/20 | 0.46 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.46 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3605523 | 0.88 | GPR119 (0.59) | GPR119PTPN11MAPTACHECKS1B | |
| SCHEMBL3607189 | 0.86 | GPR119 (0.57) | GPR119PTPN11MAPTMEN1KMT2A | |
| SCHEMBL16652717 | 0.85 | GPR119 (0.59) | GPR119PTPN11MAPTMEN1KMT2A | |
| SCHEMBL30385900 | 0.84 | HRH3 (0.59) | GPR119MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL26633205 | 0.84 | HRH3 (0.59) | GPR119MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1447826 | 0.84 | GPR119 (0.73) | GPR119MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL30385477 | 0.83 | HRH3 (0.58) | GPR119MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1447940 | 0.82 | GPR119 (0.65) | GPR119PTPN11MAPTMEN1KMT2A | |
| SCHEMBL24964179 | 0.82 | GPR119 (0.61) | GPR119PTPN11MAPTMEN1KMT2A | |
| SCHEMBL24467794 | 0.82 | GPR119 (0.57) | GPR119PTPN11MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021123291-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2021-06-24 | — | — | WO | disclosed |