Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.34 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.34 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.34 |
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2775457 | 0.89 | BTK (0.45) | BTKKDM1AMAOBMAOANFKB1 | |
| SCHEMBL2775460 | 0.89 | BTK (0.45) | BTKKDM1AMAOBMAOANFKB1 | |
| SCHEMBL24337067 | 0.84 | BTK (0.41) | BTKKDM1AMAOBMAOANFKB1 | |
| SCHEMBL22616376 | 0.84 | BTK (0.47) | BTKKDM1AMAOBMAOANFKB1 | |
| SCHEMBL31566189 | 0.84 | BTK (0.47) | BTKKDM1AMAOBMAOANFKB1 | |
| SCHEMBL25319491 | 0.81 | BTK (0.44) | BTKKDM1AMAOBMAOANFKB1 | |
| SCHEMBL27870919 | 0.81 | BTK (0.44) | BTKKDM1AMAOBMAOANFKB1 | |
| SCHEMBL21504129 | 0.79 | CTSK (0.41) | BTKKDM1AMAOBMAOANFKB1 | |
| SCHEMBL26039089 | 0.79 | KDM1A (0.40) | BTKKDM1AMAOBMAOANFKB1 | |
| SCHEMBL26783002 | 0.79 | CTSK (0.41) | BTKKDM1AMAOBMAOANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127303-A1 | PROGRANULIN MODULATORS AND METHODS OF USING THE SAME | ARKUDA THERAPEUTICS (US) | 2021-06-24 | — | — | WO | disclosed |