⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22479947 | 0.81 | — | — | |
| SCHEMBL21349639 | 0.74 | MEN1 (0.31) | — | |
| SCHEMBL24033605 | 0.72 | — | — | |
| SCHEMBL23562069 | 0.70 | — | — | |
| SCHEMBL22479922 | 0.70 | — | — | |
| SCHEMBL23560692 | 0.65 | — | — | |
| SCHEMBL23571130 | 0.61 | — | — | |
| SCHEMBL23229847 | 0.60 | — | — | |
| SCHEMBL21349642 | 0.55 | — | — | |
| SCHEMBL21660596 | 0.55 | CRBN (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021231653-A1 | MONO- AND COMBINATION THERAPIES | RECURIUM IP HOLDINGS, LLC (US) | 2021-11-18 | — | — | WO | disclosed |
| WO-2021127047-A1 | COMBINATIONS | RECURIUM IP HOLDINGS, LLC (US) | 2021-06-24 | — | — | WO | disclosed |
| WO-2021127045-A1 | COMBINATIONS | RECURIUM IP HOLDINGS, LLC (US) | 2021-06-24 | — | — | WO | disclosed |
| WO-2021127044-A1 | COMBINATIONS | RECURIUM IP HOLDINGS, LLC (US) | 2021-06-24 | — | — | WO | disclosed |