SCHEMBL2356271

SCHEMBL2356271

Oc1ccccc1CC=CBr

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 1/20 0.50
TAAR1 Q96RJ0 1/20 0.48
TSHR P16473 2/20 0.45
HIF1A Q16665 2/20 0.45
CYP2D6 P10635 1/20 0.45
AKR1B1 P15121 1/20 0.43
CA12 O43570 7/20 0.42
CA2 P00918 7/20 0.42
IDO1 P14902 2/20 0.42
CA9 Q16790 5/20 0.41
MPO P05164 2/20 0.41
KEAP1 Q14145 1/20 0.41
KDM4E B2RXH2 2/20 0.39
HSD17B10 Q99714 2/20 0.39
NPC1 O15118 1/20 0.38
GMNN O75496 1/20 0.38
ALDH1A1 P00352 1/20 0.38
EGFR P00533 1/20 0.38
LMNA P02545 1/20 0.38
FYN P06241 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11437846 0.86 HSPA5 (0.59) HSPA5TAAR1TSHRHIF1ACYP2D6
SCHEMBL9634808 0.84 MAOB (0.38) HSPA5TAAR1IDO1
SCHEMBL4931557 0.83 HSPA5 (0.50) HSPA5TAAR1TSHRHIF1ACYP2D6
SCHEMBL1349024 0.80 HSPA5 (0.52) HSPA5TAAR1TSHRHIF1ACYP2D6
SCHEMBL8578976 0.78 HSPA5 (0.50) HSPA5TAAR1TSHRHIF1ACYP2D6
SCHEMBL89100 0.78 TAAR1 (0.54) HSPA5TAAR1TSHRHIF1ACYP2D6
SCHEMBL10452220 0.78 HSPA5 (0.50) HSPA5TAAR1TSHRHIF1ACYP2D6
SCHEMBL11313250 0.78 HSPA5 (0.50) HSPA5TAAR1TSHRHIF1ACYP2D6
SCHEMBL1044191 0.78 TAAR1 (0.54) HSPA5TAAR1TSHRHIF1ACYP2D6
SCHEMBL1044190 0.78 TAAR1 (0.54) HSPA5TAAR1TSHRHIF1ACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113227290-B Silane compound and composition thereof 引能仕株式会社 2024-05-03 CN disclosed
US-11746226-B2 Polymer composition, foam and method thereof TSRC CORPORATION (TW) 2023-09-05 US disclosed
CN-111333795-B Hydrogenated block copolymer, resin composition, and article obtained using same 株式会社可乐丽 2023-04-07 CN disclosed
CN-112204059-B Hydrogenated product of block copolymer, resin composition, and various uses thereof 株式会社可乐丽 2023-02-21 CN disclosed
EP-3653651-B1 BLOCK COPOLYMER HYDROGENATE, RESIN COMPOSITION, AND APPLICATIONS THEREOF KURARAY CO (JP) 2021-08-11 EP disclosed
CN-113227290-A Silane compound and composition thereof 引能仕株式会社 2021-08-06 CN disclosed
US-20210122868-A1 HYDROGENATED BLOCK COPOLYMER, RESIN COMPOSITION, PRESSURE-SENSITIVE ADHESIVE, ADHESIVE, MOLDED OBJECT, LIQUID-PACKAGING CONTAINER, MEDICAL TOOL, MEDICAL TUBE, CORNER MEMBER FOR WEATHER SEAL, AND WEATHER SEAL KURARAY CO., LTD. (JP) 2021-04-29 US disclosed
CN-110945034-B Hydrogenated product of block copolymer, resin composition, and various uses thereof 株式会社可乐丽 2021-03-26 CN disclosed
US-10927211-B2 Block copolymer hydrogenate, resin composition, and applications thereof KURARAY CO., LTD. (JP) 2021-02-23 US disclosed
CN-107250188-B Hydrogenated block copolymer and resin composition containing same 株式会社可乐丽 2021-02-02 CN disclosed
EP-3263613-A1 HYDROGENATED BLOCK COPOLYMER, RESIN COMPOSITION, PRESSURE-SENSITIVE ADHESIVE, ADHESIVE, MOLDED OBJECT, LIQUID-PACKAGING CONTAINER, MEDICAL TOOL, MEDICAL TUBE, CORNER MEMBER FOR WEATHER SEAL, AND WEATHER SEAL Kuraray Co., Ltd. (JP) 2018-01-03 EP disclosed
US-7999038-B2 Weatherstrip SHIN-ETSU POLYMER CO., LTD. (JP) 2011-08-16 US disclosed
US-20070122570-A1 Weatherstrip SHIN-ETSU POLYMER CO., LTD. (JP) 2007-05-31 US disclosed
US-20070077375-A1 Weatherstrip SHIN-ETSU POLYMER CO., LTD. (JP) 2007-04-05 US disclosed
US-5283375-A Bromination bisphenol a in methanol solution ETHYL CORPORATION (US) 1994-02-01 US disclosed
US-5262503-A ADDITION POLYMER HAVING SPECIFIED CRYSTALLIZATION DEGREE, VISCOSITY AND MODULUS OF ELASTICITY MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JP) 1993-11-16 US disclosed
US-5202321-A Antihistamine, antiallergens, antiinflammatory agents MERCK FROSST CANADA, INC. (CA) 1993-04-13 US disclosed
EP-0518426-A1 Thiopyrano (2,3,4-c,d) indoles as inhibitors of leukotriene biosynthesis MERCK FROSST CANADA INC. (CA) 1992-12-16 EP disclosed
EP-0458731-A1 Random copolymers and crosslinked products of te same MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JP) 1991-11-27 EP disclosed
US-4260803-A FIREPROOFING, HERBICIDES, FUNGICIDES DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1981-04-07 US disclosed