Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITPR3 | Q14573 | 8/20 | 0.45 |
| ▸ | ITPR2 | Q14571 | 3/20 | 0.45 |
| ▸ | ITPR1 | Q14643 | 3/20 | 0.45 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.41 |
| ▸ | INPP5A | Q14642 | 1/20 | 0.39 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8582671 | 1.00 | ITPR3 (0.45) | ITPR3ITPR2ITPR1SMPD1INPP5A | |
| SCHEMBL1065994 | 1.00 | ITPR3 (0.45) | ITPR3ITPR2ITPR1SMPD1INPP5A | |
| SCHEMBL5523617 | 1.00 | ITPR3 (0.45) | ITPR3ITPR2ITPR1SMPD1INPP5A | |
| SCHEMBL30240916 | 1.00 | ITPR3 (0.45) | ITPR3ITPR2ITPR1SMPD1INPP5A | |
| SCHEMBL8581971 | 1.00 | ITPR3 (0.45) | ITPR3ITPR2ITPR1SMPD1INPP5A | |
| SCHEMBL23563167 | 1.00 | ITPR3 (0.45) | ITPR3ITPR2ITPR1SMPD1INPP5A | |
| SCHEMBL9300366 | 1.00 | ITPR3 (0.45) | ITPR3ITPR2ITPR1SMPD1INPP5A | |
| SCHEMBL14437195 | 1.00 | ITPR3 (0.45) | ITPR3ITPR2ITPR1SMPD1INPP5A | |
| SCHEMBL14268493 | 1.00 | ITPR3 (0.45) | ITPR3ITPR2ITPR1SMPD1INPP5A | |
| SCHEMBL7529773 | 1.00 | ITPR3 (0.45) | ITPR3ITPR2ITPR1SMPD1INPP5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127414-A1 | USE OF FUCOSYLATION INHIBITOR FOR PRODUCING AFUCOSYLATED ANTIBODY | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-06-24 | — | — | WO | disclosed |