SCHEMBL2356366

SCHEMBL2356366

CCOC(COC(=O)C(C)=CO)OCC

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.33
GLO1 Q04760 1/20 0.33
ALDH1A1 P00352 3/20 0.32
LMNA P02545 1/20 0.32
HSD17B10 Q99714 1/20 0.32
CYP2D6 P10635 2/20 0.31
CYP2C19 P33261 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2296930 0.87 TSHR (0.34) TSHRGLO1ALDH1A1LMNAHSD17B10
SCHEMBL26628998 0.82 CYP2D6 (0.33) TSHRGLO1ALDH1A1LMNAHSD17B10
SCHEMBL8306704 0.78
SCHEMBL2346338 0.78
SCHEMBL79140 0.78
SCHEMBL2289378 0.77 TSHR (0.59) TSHRGLO1ALDH1A1LMNAHSD17B10
SCHEMBL6062547 0.76 TSHR (0.57) TSHRALDH1A1HSD17B10CYP2D6CYP2C19
SCHEMBL5390019 0.76 GLO1 (0.50) TSHRGLO1ALDH1A1LMNAHSD17B10
SCHEMBL5390016 0.76 GLO1 (0.50) TSHRGLO1ALDH1A1LMNAHSD17B10
SCHEMBL10539079 0.76 GLO1 (0.50) TSHRGLO1ALDH1A1LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023215886-A1 ENGINEERED PARTICLES AS RED BLOOD CELL MIMICS AND COMPOSITIONS CONTAINING SAME FOR HEMATOLOGY SLINGSHOT BIOSCIENCES, INC. (US) 2023-11-09 WO claimed
EP-2349459-A1 TREATMENT OF SWEATING AND HYPERHIDROSIS Johnson & Johnson Consumer Companies, Inc. (US) 2011-08-03 EP disclosed
WO-2010027792-A1 TREATMENT OF SWEATING AND HYPERHIDROSIS JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2010-03-11 WO disclosed