Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP26A1 | O43174 | 4/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23563999 | 0.89 | MAPT (0.69) | MAPTCYP3A4KMT2AMEN1TSHR | |
| SCHEMBL23529438 | 0.87 | MAPT (0.67) | MAPTCYP3A4KMT2AMEN1TSHR | |
| SCHEMBL29767719 | 0.87 | MAPT (0.67) | MAPTCYP3A4KMT2AMEN1TSHR | |
| SCHEMBL5364455 | 0.84 | MAPT (0.77) | MAPTCYP3A4KMT2AMEN1TSHR | |
| SCHEMBL9824981 | 0.81 | MAPT (1.00) | MAPTCYP3A4KMT2AMEN1CYP24A1 | |
| SCHEMBL28829964 | 0.81 | MAPT (0.58) | MAPTCYP3A4KMT2AMEN1TSHR | |
| SCHEMBL23564144 | 0.80 | MAPT (0.64) | MAPTCYP3A4KMT2AMEN1TSHR | |
| SCHEMBL11366095 | 0.79 | MAPT (0.77) | MAPTCYP3A4KMT2AMEN1TSHR | |
| SCHEMBL23564157 | 0.76 | KMT2A (0.71) | MAPTCYP3A4KMT2AMEN1TDP1 | |
| SCHEMBL11466661 | 0.76 | MAPT (0.61) | MAPTCYP3A4KMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113004247-B | Triazole derivative and application thereof | 沈阳化工研究院有限公司 | 2023-04-07 | — | — | CN | disclosed |
| WO-2021120992-A1 | TRIAZOLE DERIVATIVES AND APPLICATION THEREOF | 沈阳化工研究院有限公司 | 2021-06-24 | — | — | WO | disclosed |
| CN-113004247-A | Triazole derivative and application thereof | 沈阳化工研究院有限公司 | 2021-06-22 | — | — | CN | disclosed |