Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 8/20 | 0.60 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.60 |
| ▸ | CDK1 | P06493 | 2/20 | 0.60 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.60 |
| ▸ | GSK3A | P49840 | 2/20 | 0.60 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.60 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.60 |
| ▸ | CDK2 | P24941 | 1/20 | 0.60 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.60 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.60 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.60 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.60 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.60 |
| ▸ | IDH1 | O75874 | 3/20 | 0.38 |
| ▸ | ROS1 | P08922 | 1/20 | 0.35 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 5/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Laduviglusib SCHEMBL29381114 | 0.88 | GSK3B (0.77) | GSK3BCCNB2CDK1CCNB1GSK3A | |
| Laduviglusib SCHEMBL29838591 | 0.88 | GSK3B (0.77) | GSK3BCCNB2CDK1CCNB1GSK3A | |
| Laduviglusib SCHEMBL240280 | 0.88 | GSK3B (0.77) | GSK3BCCNB2CDK1CCNB1GSK3A | |
| SCHEMBL4404427 | 0.87 | GSK3B (0.64) | GSK3BCCNB2CDK1CCNB1GSK3A | |
| Laduviglusib SCHEMBL17165152 | 0.87 | GSK3B (0.76) | GSK3BCCNB2CDK1CCNB1GSK3A | |
| SCHEMBL12552315 | 0.81 | GSK3B (0.67) | GSK3BCCNB2CDK1CCNB1GSK3A | |
| SCHEMBL5094723 | 0.80 | GSK3B (0.66) | GSK3BCCNB2CDK1CCNB1GSK3A | |
| SCHEMBL4398952 | 0.80 | GSK3B (0.65) | GSK3BCCNB2CDK1CCNB1GSK3A | |
| SCHEMBL20095066 | 0.78 | GSK3B (0.72) | GSK3BCCNB2CDK1CCNB1GSK3A | |
| SCHEMBL7148131 | 0.77 | GSK3B (0.71) | GSK3BCCNB2CDK1CCNB1GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210189335-A1 | OLIGODENDROCYTE PROGENITOR CELL COMPOSITIONS | ASTERIAS BIOTHERAPEUTICS, INC. (US) | 2021-06-24 | — | — | US | disclosed |