Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | HRH2 | P25021 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31670126 | 0.78 | GBA1 (0.40) | GBA1HSD11B1 | |
| SCHEMBL12409052 | 0.78 | HSD11B1 (0.41) | GBA1HSD11B1CNR2HRH2HRH1 | |
| SCHEMBL20231747 | 0.78 | GBA1 (0.37) | GBA1HSD11B1 | |
| SCHEMBL20070438 | 0.76 | GBA1 (0.33) | GBA1HSD11B1 | |
| SCHEMBL25026076 | 0.75 | HSD11B1 (0.40) | GBA1HSD11B1CNR2 | |
| SCHEMBL20683622 | 0.74 | GBA1 (0.35) | GBA1HSD11B1HRH3 | |
| SCHEMBL25670157 | 0.74 | GBA1 (0.35) | GBA1HSD11B1 | |
| SCHEMBL23640178 | 0.74 | GBA1 (0.37) | GBA1HSD11B1 | |
| SCHEMBL24996666 | 0.74 | GBA1 (0.33) | GBA1HSD11B1 | |
| SCHEMBL25026075 | 0.74 | HSD11B1 (0.39) | GBA1HSD11B1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127499-A1 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | CALICO LIFE SCIENCES LLC (US) | 2021-06-24 | — | — | WO | disclosed |