Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.49 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | NAAA | Q02083 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15981157 | 0.98 | USP2 (0.56) | USP2HTTLPAR5SPHK1CYP1A2 | |
| SCHEMBL18274656 | 0.91 | USP2 (0.69) | USP2HTTLPAR5SPHK1CYP1A2 | |
| SCHEMBL20794136 | 0.85 | USP2 (0.50) | USP2HTTLPAR5KDM4EMAPT | |
| SCHEMBL14113926 | 0.83 | KDM4E (0.44) | HTTKDM4EMAPTALDH1A1APOBEC3A | |
| SCHEMBL300014 | 0.80 | USP2 (0.76) | USP2HTTLPAR5SPHK1CYP1A2 | |
| SCHEMBL13907638 | 0.80 | KDM4E (0.49) | HTTKDM4EMAPTALDH1A1APOBEC3A | |
| SCHEMBL13190990 | 0.79 | KDM4E (0.47) | HTTKDM4EMAPTALDH1A1APOBEC3A | |
| SCHEMBL16004180 | 0.79 | KDM4E (0.47) | HTTKDM4EMAPTALDH1A1APOBEC3A | |
| SCHEMBL13191295 | 0.79 | KDM4E (0.47) | HTTKDM4EMAPTALDH1A1APOBEC3A | |
| SCHEMBL9117095 | 0.78 | USP2 (0.80) | USP2HTTLPAR5SPHK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210187476-A1 | Chromatography Beads, Production and Use Threreof | CYTIVA BIOPROCESS R&D AB (SE) | 2021-06-24 | — | — | US | disclosed |