Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | RGS12 | O14924 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18274656 | 0.90 | USP2 (0.69) | USP2KDM4EMAPTHTTLMNA | |
| SCHEMBL3815044 | 0.88 | KDM4E (0.45) | USP2KDM4EPRMT5WDR77MAPT | |
| SCHEMBL9132499 | 0.88 | KDM4E (0.45) | USP2KDM4EPRMT5WDR77MAPT | |
| Water SCHEMBL29022494 | 0.86 | KDM4E (0.44) | USP2KDM4EPRMT5WDR77MAPT | |
| SCHEMBL8534128 | 0.86 | KDM4E (0.43) | USP2KDM4EPRMT5WDR77MAPT | |
| SCHEMBL23564645 | 0.85 | USP2 (0.53) | USP2KDM4EPRMT5WDR77MAPT | |
| SCHEMBL15981157 | 0.84 | USP2 (0.56) | USP2KDM4EMAPTHTTALDH1A1 | |
| SCHEMBL22631553 | 0.82 | HTT (0.40) | USP2KDM4EPRMT5WDR77MAPT | |
| SCHEMBL13907638 | 0.82 | KDM4E (0.49) | KDM4EPRMT5WDR77MAPTHTT | |
| SCHEMBL20881774 | 0.79 | KDM4E (0.38) | KDM4EPRMT5WDR77MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190071517-A1 | RECOGNITION OF MEMBRANE TYPE MUCIN-LIKE PROTEIN AND CLINICAL APPLICATION THEREOF | KANAGAWA PREFECTURAL HOSPITAL ORGANIZATION (JP) | 2019-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190071517-A1 | RECOGNITION OF MEMBRANE TYPE MUCIN-LIKE PROTEIN AND CLINICAL APPLICATION THEREOF | MUC1, CD44, EPCAM | USP2 1191/4885KDM4E 2212/4885PRMT5 837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.