Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | PLA2G4B | P0C869 | 8/20 | 0.62 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.60 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2362233 | 1.00 | RARB (0.67) | RARBTP53TSHRPLA2G4BPTPN11 | |
| SCHEMBL12243195 | 0.91 | GAA (0.55) | RARBTP53TSHRPLA2G4BPTPN11 | |
| SCHEMBL16199805 | 0.91 | RARB (0.53) | RARBTP53TSHRPLA2G4BPTPN11 | |
| SCHEMBL12243186 | 0.91 | GAA (0.55) | RARBTP53TSHRPLA2G4BPTPN11 | |
| SCHEMBL12294464 | 0.90 | RARB (0.52) | RARBTP53TSHRPLA2G4BPTPN11 | |
| SCHEMBL2357337 | 0.89 | RARB (0.51) | RARBTP53TSHRPLA2G4BPTPN11 | |
| SCHEMBL12243294 | 0.89 | RARB (0.51) | RARBTP53TSHRPLA2G4BPTPN11 | |
| SCHEMBL12243345 | 0.88 | RARB (0.50) | RARBTP53TSHRPLA2G4BPTPN11 | |
| SCHEMBL12243297 | 0.87 | PLA2G4B (0.52) | RARBTP53PLA2G4BKDM4ENPC1 | |
| SCHEMBL12243098 | 0.86 | RARB (0.47) | RARBTP53TSHRPLA2G4BPTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8921309-B2 | Lipopeptide compounds and their use | UNIQUEST PTY LIMITED (AU) | 2014-12-30 | — | — | US | disclosed |
| EP-2350119-B1 | LIPOPEPTIDE COMPOUNDS AND THEIR USE | UNIQUEST PTY LTD (AU) | 2014-10-29 | — | — | EP | disclosed |
| US-20110224129-A1 | Lipopeptide Compounds and Their Use | MERLION PHARMACEUTICALS PTE LTD (SG) | 2011-09-15 | — | — | US | disclosed |
| EP-2350119-A1 | LIPOPEPTIDE COMPOUNDS AND THEIR USE | Merlion Pharmaceuticals Pte Ltd. (SG) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010062264-A1 | LIPOPEPTIDE COMPOUNDS AND THEIR USE | MERLION PHARMACEUTICALS PTE LTD (SG) | 2010-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224129-A1 | Lipopeptide Compounds and Their Use | VIP, LTA, CLPTM1 | RARB 2792/4885TP53 3875/4885TSHR 2537/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.