Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | STAT1 | P42224 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | CCR8 | P51685 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6798000 | 0.79 | GPR119 (0.44) | GPR119NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL23564938 | 0.79 | GPR119 (0.44) | GPR119NPC1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL20639995 | 0.79 | GPR119 (0.44) | GPR119ALDH1A1HTTHSD17B10TDP1 | |
| SCHEMBL23539553 | 0.79 | GPR119 (0.44) | GPR119RAB9AALDH1A1HTTHSD17B10 | |
| SCHEMBL21382262 | 0.74 | EGLN2 (0.41) | GPR119NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL1618003 | 0.74 | HTT (0.50) | GPR119NPC1RAB9APKMSMN1; SMN2 | |
| SCHEMBL17525081 | 0.73 | GPR119 (0.46) | GPR119GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL21385028 | 0.72 | GPR119 (0.41) | GPR119ALDH1A1HTTHSD17B10TDP1 | |
| SCHEMBL30947099 | 0.72 | GPR119 (0.41) | GPR119ALDH1A1HTTHSD17B10TDP1 | |
| SCHEMBL23564965 | 0.71 | HTT (0.44) | GPR119NPC1RAB9APKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127459-A1 | GPR139 RECEPTOR MODULATORS | BLACKTHORN THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |