Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | NQO2 | P16083 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | TOP1 | P11387 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PRNP | P04156 | 1/20 | 0.30 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
| ▸ | TOP2A | P11388 | 1/20 | 0.30 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23566021 | 0.89 | ALDH1A1 (0.41) | ALDH1A1HPGDMEN1GLAMAPT | |
| SCHEMBL23566323 | 0.78 | NQO2 (0.58) | ALDH1A1HPGDNQO2HSD17B10TOP1 | |
| SCHEMBL23566320 | 0.75 | NQO2 (0.65) | ALDH1A1HPGDNQO2HSD17B10TOP1 | |
| SCHEMBL23566022 | 0.70 | NQO2 (0.50) | ALDH1A1HPGDMAPTNQO2HSD17B10 | |
| SCHEMBL23566266 | 0.68 | ALDH1A1 (0.38) | ALDH1A1HPGDMEN1GLAMAPT | |
| SCHEMBL395347 | 0.67 | NQO2 (0.63) | ALDH1A1HPGDNQO2HSD17B10TOP1 | |
| SCHEMBL23566261 | 0.66 | ALDH1A1 (0.47) | ALDH1A1HPGDMEN1GLAMAPT | |
| SCHEMBL23566335 | 0.64 | NQO2 (0.73) | ALDH1A1HPGDNQO2HSD17B10TOP1 | |
| SCHEMBL7352974 | 0.63 | NQO2 (0.65) | ALDH1A1HPGDMAPTNQO2HSD17B10 | |
| Hydrochloric Acid SCHEMBL10463751 | 0.62 | ALDH1A1 (0.67) | ALDH1A1HPGDMAPTNQO2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127452-A1 | COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS AND POTENTIATION OF ANTIBIOTICS | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2021-06-24 | — | — | WO | disclosed |