SCHEMBL23567307

SCHEMBL23567307

C#CCCOCOCCCC

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
CYP3A4 P08684 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
HPGD P15428 1/20 0.33
ADRB2 P07550 1/20 0.33
ADRB1 P08588 1/20 0.33
ADRB3 P13945 1/20 0.33
ACHE P22303 1/20 0.32
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31
MEN1 O00255 1/20 0.31
THRB P10828 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23567214 0.93 HTT (0.39) TSHRSMN1; SMN2MEN1THRBHTT
SCHEMBL23567289 0.91 HTT (0.42) TSHRSMN1; SMN2MEN1THRBHTT
SCHEMBL23567257 0.91 HTT (0.42) TSHRSMN1; SMN2MEN1THRBHTT
SCHEMBL23567223 0.91 HTT (0.42) TSHRSMN1; SMN2MEN1THRBHTT
SCHEMBL23567269 0.91 HTT (0.42) TSHRSMN1; SMN2MEN1THRBHTT
SCHEMBL23567246 0.91 HTT (0.42) TSHRSMN1; SMN2MEN1THRBHTT
SCHEMBL23567300 0.91 TSHR (0.39) TSHRCYP3A4SMN1; SMN2HPGDADRB2
SCHEMBL16645786 0.91
SCHEMBL23567249 0.89 TSHR (0.38) TSHRCYP3A4SMN1; SMN2HPGDADRB2
SCHEMBL23567226 0.87 MAPT (0.38) TSHRCYP3A4SMN1; SMN2HPGDADRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12060323-B2 6-hydroxy-3-hexenyl alkoxymethyl ether compound and a process for preparing a 3,13-octadecadien-1-ol compound from the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-08-13 US disclosed
CN-113024359-B Process for preparing alkoxymethyl alkynyl ether compounds having terminal triple bonds 信越化学工业株式会社 2024-06-11 CN disclosed
EP-3842406-B1 PROCESS FOR PREPARING AN ALKOXYMETHYL ALKYNYL ETHER COMPOUND HAVING A TERMINAL TRIPLE BOND SHINETSU CHEMICAL CO (JP) 2023-10-11 EP disclosed
US-20230312454-A1 6-HYDROXY-3-HEXENYL ALKOXYMETHYL ETHER COMPOUND AND A PROCESS FOR PREPARING A 3,13-OCTADECADIEN-1-OL COMPOUND FROM THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-10-05 US disclosed
US-20230312454-A1 6-HYDROXY-3-HEXENYL ALKOXYMETHYL ETHER COMPOUND AND A PROCESS FOR PREPARING A 3,13-OCTADECADIEN-1-OL COMPOUND FROM THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-10-05 US disclosed
EP-3978465-B1 6-HYDROXY-3-HEXENYL ALKOXYMETHYL ETHER COMPOUND AND A PROCESS FOR PREPARING A 3,13-OCTADECADIEN-1-OL COMPOUND FROM THE SAME SHINETSU CHEMICAL CO (JP) 2023-06-14 EP disclosed
US-11661394-B2 6-hydroxy-3-hexenyl alkoxymethyl ether compound and a process for preparing a 3,13-octadecadien-1-ol compound from the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-05-30 US disclosed
US-11384041-B2 Process for preparing an alkoxymethyl alkynyl ether compound having a terminal triple bond SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-07-12 US disclosed
CN-114380669-A 6-hydroxy-3-hexenylalkoxymethyl ether compounds and process for preparing 3, 13-octadecadien-1-ol therefrom 信越化学工业株式会社 2022-04-22 CN disclosed
US-20220106252-A1 6-HYDROXY-3-HEXENYL ALKOXYMETHYL ETHER COMPOUND AND A PROCESS FOR PREPARING A 3,13-OCTADECADIEN-1-OL COMPOUND FROM THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-04-07 US disclosed
US-20210198172-A1 PROCESS FOR PREPARING AN ALKOXYMETHYL ALKYNYL ETHER COMPOUND HAVING A TERMINAL TRIPLE BOND SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-07-01 US disclosed
EP-3842406-A1 PROCESS FOR PREPARING AN ALKOXYMETHYL ALKYNYL ETHER COMPOUND HAVING A TERMINAL TRIPLE BOND Shin-Etsu Chemical Co., Ltd. (JP) 2021-06-30 EP disclosed
CN-113024359-A Method for producing alkoxymethyl alkynyl ether compounds having terminal triple bond 信越化学工业株式会社 2021-06-25 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11661394-B2 6-hydroxy-3-hexenyl alkoxymethyl ether compound and a process for preparing a 3,13-octadecadien-1-ol compound from the same CYP8B1, OXER1, CYP2E1 TSHR 2178/4885CYP3A4 82/4885SMN1; SMN2 3662/4885
US-20210198172-A1 PROCESS FOR PREPARING AN ALKOXYMETHYL ALKYNYL ETHER COMPOUND HAVING A TERMINAL TRIPLE BOND CBR3, CBR1, AOC2 TSHR 2045/4885CYP3A4 380/4885SMN1; SMN2 3687/4885
US-12060323-B2 6-hydroxy-3-hexenyl alkoxymethyl ether compound and a process for preparing a 3,13-octadecadien-1-ol compound from the same CYP8B1, CYP2E1, OXER1 TSHR 2266/4885CYP3A4 70/4885SMN1; SMN2 3680/4885
US-11384041-B2 Process for preparing an alkoxymethyl alkynyl ether compound having a terminal triple bond CBR3, CBR1, AOC2 TSHR 2045/4885CYP3A4 380/4885SMN1; SMN2 3687/4885
US-20230312454-A1 6-HYDROXY-3-HEXENYL ALKOXYMETHYL ETHER COMPOUND AND A PROCESS FOR PREPARING A 3,13-OCTADECADIEN-1-OL COMPOUND FROM THE SAME CYP8B1, CYP2E1, OXER1 TSHR 2358/4885CYP3A4 83/4885SMN1; SMN2 3674/4885
US-20220106252-A1 6-HYDROXY-3-HEXENYL ALKOXYMETHYL ETHER COMPOUND AND A PROCESS FOR PREPARING A 3,13-OCTADECADIEN-1-OL COMPOUND FROM THE SAME CYP8B1, OXER1, CYP2E1 TSHR 2178/4885CYP3A4 82/4885SMN1; SMN2 3662/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.