Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 8/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.35 |
| ▸ | SPPL2A | Q8TCT8 | 2/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27658769 | 0.81 | ALDH1A1 (0.51) | KMT2AMEN1KDM4EALDH1A1HTR2A | |
| SCHEMBL2312046 | 0.75 | PARG (0.45) | KMT2AMEN1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL1326995 | 0.74 | PARG (0.44) | KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL5531315 | 0.74 | ALDH1A1 (0.65) | KMT2AMEN1KDM4EALDH1A1HTR2A | |
| SCHEMBL493016 | 0.74 | OPRL1 (0.42) | KDM4EALDH1A1HTR2A | |
| SCHEMBL13903208 | 0.71 | GAA (0.47) | KMT2AMEN1HTR2AGAAL3MBTL1 | |
| SCHEMBL17900515 | 0.71 | GAA (0.47) | KMT2AMEN1HTR2AGAAL3MBTL1 | |
| SCHEMBL18596065 | 0.71 | IDO1 (0.41) | KDM4EALDH1A1HTR2AGAAL3MBTL1 | |
| SCHEMBL22012424 | 0.71 | HTR2A (0.35) | ALDH1A1HTR2AHTR2CL3MBTL1PSEN1 | |
| SCHEMBL643245 | 0.70 | IDO1 (0.38) | KDM4EALDH1A1HTR2AGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1989174-B1 | SUBSTITUTED CYCLOHEXYLMETHYL DERIVATIVES | GRUENENTHAL GMBH (DE) | 2011-08-03 | — | — | EP | claimed |