Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | PTP4A3 | O75365 | 2/20 | 0.38 |
| ▸ | TDP2 | O95551 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | PTP4A2 | Q12974 | 1/20 | 0.36 |
| ▸ | PTP4A1 | Q93096 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16546079 | 0.84 | HSD17B1 (0.41) | HSD17B1ESR1PTP4A3TDP2PTP4A2 | |
| SCHEMBL23568683 | 0.75 | HSD17B1 (0.36) | HSD17B1ESR1PTP4A3PTP4A2PTP4A1 | |
| SCHEMBL31497079 | 0.73 | HSP90AA1 (0.46) | HSP90AA1CA1CA2CA4CA6 | |
| SCHEMBL23568424 | 0.72 | PTP4A3 (0.38) | HSD17B1ESR1PTP4A3PTP4A2PTP4A1 | |
| SCHEMBL17368871 | 0.71 | PTP4A3 (0.40) | HSD17B1ESR1PTP4A3CNR1PTP4A2 | |
| SCHEMBL1922789 | 0.71 | METAP1 (0.57) | HSP90AA1CA1CA2CA4CA6 | |
| SCHEMBL29572171 | 0.71 | METAP1 (0.57) | HSP90AA1CA1CA2CA4CA6 | |
| SCHEMBL23568061 | 0.71 | PTP4A3 (0.50) | HSP90AA1HSD17B1ESR1PTP4A3PTP4A2 | |
| SCHEMBL11525349 | 0.70 | HSD17B1 (0.58) | HSD17B1ESR1PTP4A3PTP4A2PTP4A1 | |
| SCHEMBL11521978 | 0.70 | HSD17B1 (0.58) | HSD17B1ESR1PTP4A3PTP4A2PTP4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230138100-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-05-04 | — | — | US | disclosed |
| US-20230138100-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-05-04 | — | — | US | disclosed |
| WO-2021122868-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2021-06-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230138100-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | CYP2C19, ETV6, ESR1 | HSP90AA1 4393/4885CA1 3218/4885CA2 4313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.