Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.45 |
| ▸ | RXRA | P19793 | 2/20 | 0.40 |
| ▸ | RXRB | P28702 | 2/20 | 0.40 |
| ▸ | RXRG | P48443 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 5/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23570086 | 0.84 | MRGPRX4 (0.46) | MRGPRX4RXRARXRBRXRGCES2 | |
| SCHEMBL23531157 | 0.84 | MRGPRX4 (0.46) | MRGPRX4RXRARXRBRXRGCES2 | |
| SCHEMBL23570087 | 0.82 | MRGPRX4 (0.48) | MRGPRX4RXRARXRBRXRGCES2 | |
| SCHEMBL23570081 | 0.79 | MRGPRX4 (0.43) | MRGPRX4RXRARXRBRXRGCES2 | |
| SCHEMBL17897037 | 0.78 | MRGPRX4 (0.51) | MRGPRX4RXRARXRBRXRGCES2 | |
| SCHEMBL23570088 | 0.77 | TPMT (0.50) | MRGPRX4RXRARXRBRXRGTSHR | |
| SCHEMBL27761970 | 0.76 | RXRA (0.53) | MRGPRX4RXRARXRBRXRGCES2 | |
| SCHEMBL17896574 | 0.75 | MRGPRX4 (0.49) | MRGPRX4RXRARXRBRXRGCES2 | |
| SCHEMBL16019241 | 0.75 | MRGPRX4 (0.49) | MRGPRX4RXRARXRBRXRGCES2 | |
| SCHEMBL2993355 | 0.74 | MRGPRX4 (0.51) | MRGPRX4RXRARXRBRXRGCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021122645-A1 | PESTICIDALLY ACTIVE AZOLE-AMIDE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2021-06-24 | — | — | WO | disclosed |