Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23571999 | 0.81 | MEN1 (0.31) | — | |
| SCHEMBL13086589 | 0.72 | KDM5B (0.32) | KDM5B | |
| SCHEMBL14701602 | 0.72 | KDM5B (0.33) | KDM5B | |
| SCHEMBL798899 | 0.69 | KDM5B (0.33) | KDM5B | |
| SCHEMBL15767066 | 0.68 | SUV39H2 (0.32) | — | |
| SCHEMBL12269121 | 0.68 | SCN10A (0.30) | — | |
| SCHEMBL26127567 | 0.67 | CCR1 (0.32) | — | |
| SCHEMBL23571485 | 0.67 | RXFP1 (0.47) | — | |
| SCHEMBL14701746 | 0.67 | KDM5B (0.32) | KDM5B | |
| SCHEMBL14701603 | 0.67 | GRM5 (0.33) | KDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021126729-A1 | PRMT5 INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2021-06-24 | — | — | WO | disclosed |