Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL798899 | 0.81 | KDM5B (0.33) | GRM5KDM5B | |
| SCHEMBL14701602 | 0.80 | KDM5B (0.33) | KDM5B | |
| SCHEMBL14701746 | 0.79 | KDM5B (0.32) | GRM5KDM5B | |
| SCHEMBL12443626 | 0.76 | GRM5 (0.39) | GRM5 | |
| SCHEMBL23571869 | 0.73 | GPR139 (0.31) | — | |
| SCHEMBL12197120 | 0.69 | APP (0.46) | GRM5 | |
| SCHEMBL12196880 | 0.69 | ALDH1A1 (0.49) | — | |
| SCHEMBL23571867 | 0.68 | CDK4 (0.32) | GRM5 | |
| SCHEMBL2326296 | 0.68 | PTGS1 (0.41) | GRM5 | |
| SCHEMBL23572001 | 0.67 | KDM5B (0.30) | KDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9284350-B2 | IAP BIR domain binding compounds | PHARMASCIENCE INC. (CA) | 2016-03-15 | — | — | US | disclosed |
| US-20130040892-A1 | IAP BIR DOMAIN BINDING COMPOUNDS | PHARMASCIENCE INC. (CA) | 2013-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130040892-A1 | IAP BIR DOMAIN BINDING COMPOUNDS | BIRC5, BIRC2, BIRC3 | GRM5 4825/4885KDM5B 3284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.