Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | CFD | P00746 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CCR6 | P51684 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6862380 | 0.86 | EPHX2 (0.58) | ALDH1A1SMN1; SMN2EPHX2KMT2AMAPT | |
| SCHEMBL257808 | 0.86 | EPHX2 (0.58) | ALDH1A1SMN1; SMN2EPHX2KMT2AMAPT | |
| SCHEMBL3264202 | 0.84 | GAA (0.56) | ALDH1A1SMN1; SMN2KMT2ALMNAMAPT | |
| SCHEMBL12351159 | 0.84 | ALDH1A1 (0.48) | ALDH1A1USP2SMN1; SMN2EPHX2KMT2A | |
| SCHEMBL18343188 | 0.83 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2LMNAMAPTNPC1 | |
| SCHEMBL424884 | 0.83 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2KMT2AMEN1HPGD | |
| SCHEMBL5675377 | 0.83 | PDGFRB (0.58) | SMN1; SMN2EPHX2KMT2ALMNAMAPT | |
| SCHEMBL7139795 | 0.83 | CA1 (0.48) | KMT2AMEN1POLBLPLLIPG | |
| SCHEMBL2355851 | 0.82 | SMN1; SMN2 (0.47) | SMN1; SMN2EPHX2KMT2ANPC1RAB9A | |
| SCHEMBL12350704 | 0.81 | KCNK3 (0.58) | KMT2AMEN1HPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011101640-A1 | FUSED HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF MALARIA | MEDICAL RESEARCH COUNCIL TECHNOLOGY (GB) | 2011-08-25 | — | — | WO | disclosed |