SCHEMBL23579337

SCHEMBL23579337

[N-]=[N+]=NCCOC(=O)NCCCC[C@@H](N)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DDAH1 O94760 4/20 0.43
▸ OTC P00480 1/20 0.42
▸ DPP8 Q6V1X1 2/20 0.39
▸ DPP7 Q9UHL4 2/20 0.39
▸ DPP4 P27487 1/20 0.39
▸ NOS2 P35228 6/20 0.38
▸ NOS1 P29475 4/20 0.38
▸ NOS3 P29474 3/20 0.38
▸ CYP1A2 P05177 2/20 0.38
▸ TSHR P16473 2/20 0.38
▸ CYP3A4 P08684 1/20 0.38
▸ GSR P00390 1/20 0.38
▸ CYP2C19 P33261 2/20 0.38
▸ GLA P06280 1/20 0.38
▸ NFKB1 P19838 1/20 0.38
▸ APEX1 P27695 1/20 0.38
▸ BLM P54132 1/20 0.38
▸ ANPEP P15144 1/20 0.36
▸ ACHE P22303 1/20 0.36
▸ MEN1 O00255 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15546760 1.00 DDAH1 (0.43) DDAH1OTCDPP8DPP7DPP4
SCHEMBL15618248 1.00 DDAH1 (0.43) DDAH1OTCDPP8DPP7DPP4
Hydrochloric Acid SCHEMBL23629020 0.99 DDAH1 (0.42) DDAH1OTCDPP8DPP7DPP4
Hydrochloric Acid SCHEMBL23629018 0.99 DDAH1 (0.42) DDAH1OTCDPP8DPP7DPP4
SCHEMBL20178606 0.96 OTC (0.46) DDAH1OTCDPP8DPP7DPP4
SCHEMBL16446997 0.96 OTC (0.46) DDAH1OTCDPP8DPP7DPP4
SCHEMBL16446646 0.94 DDAH1 (0.42) DDAH1OTCDPP8DPP7DPP4
SCHEMBL15618151 0.91 DDAH1 (0.42) DDAH1OTCNOS2NOS1NOS3
SCHEMBL15618277 0.90 DDAH1 (0.43) DDAH1OTCNOS2NOS1NOS3
SCHEMBL15618149 0.90 DDAH1 (0.43) DDAH1OTCNOS2NOS1NOS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12577197-B2 Methods of preparing N6-((2-azidoethoxy)carbonyl)lysine SANOFI (FR) 2026-03-17 — — US disclosed
US-12577197-B2 Methods of preparing N6-((2-azidoethoxy)carbonyl)lysine SANOFI (FR) 2026-03-17 — — US disclosed
WO-2023029416-A1 HUMAN INTERLEUKIN 2-POLYETHYLENE GLYCOL CONJUGATE AND APPLICATION THEREOF 浙江新码生物医药有限公司 2023-03-09 — — WO disclosed
WO-2023004687-A1 UNNATURAL AMINO ACID AND APPLICATION THEREOF, RECOMBINANT PROTEIN CONTAINING SAME, AND RECOMBINANT PROTEIN CONJUGATE 浙江新码生物医药有限公司 2023-02-02 — — WO disclosed
WO-2023004686-A1 UNNATURAL AMINO ACID, AND USE THEREOF, RECOMBINANT PROTEIN CONTAINING SAME, AND RECOMBINANT PROTEIN CONJUGATE 浙江新码生物医药有限公司 2023-02-02 — — WO disclosed
US-20220324792-A1 METHODS OF PREPARING N6-((2-AZIDOETHOXY)CARBONYL)LYSINE Synthorx, Inc. (US) 2022-10-13 — — US disclosed
US-20220324792-A1 METHODS OF PREPARING N6-((2-AZIDOETHOXY)CARBONYL)LYSINE Synthorx, Inc. (US) 2022-10-13 — — US disclosed
CN-115087634-A Method for preparing N6- ((2-azidoethoxy) carbonyl) lysine 新索思股份有限公司 2022-09-20 — — CN disclosed
CN-115087634-A Method for preparing N6- ((2-azidoethoxy) carbonyl) lysine 新索思股份有限公司 2022-09-20 — — CN disclosed
WO-2021133839-A1 METHODS OF PREPARING N6-((2-AZIDOETHOXY)CARBONYL)LYSINE Synthorx, Inc. (US) 2021-07-01 — — WO disclosed
WO-2021133839-A1 METHODS OF PREPARING N6-((2-AZIDOETHOXY)CARBONYL)LYSINE Synthorx, Inc. (US) 2021-07-01 — — WO disclosed
WO-2021133839-A1 METHODS OF PREPARING N6-((2-AZIDOETHOXY)CARBONYL)LYSINE Synthorx, Inc. (US) 2021-07-01 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220324792-A1 METHODS OF PREPARING N6-((2-AZIDOETHOXY)CARBONYL)LYSINE JMJD6, LOX, KDM6B DDAH1 2190/4885OTC 82/4885DPP8 1242/4885
US-12577197-B2 Methods of preparing N6-((2-azidoethoxy)carbonyl)lysine JMJD6, PHF2, KDM2A DDAH1 1931/4885OTC 180/4885DPP8 3839/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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