Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23609749 | 0.94 | ALDH1A1 (0.48) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL29973231 | 0.94 | ALDH1A1 (0.48) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL23579288 | 0.84 | ALDH1A1 (0.60) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL29973226 | 0.84 | ALDH1A1 (0.60) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL25784498 | 0.84 | ALDH1A1 (0.54) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL29973233 | 0.82 | ALDH1A1 (0.45) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL25784490 | 0.82 | ALDH1A1 (0.45) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL23609373 | 0.81 | NR1H2 (0.38) | POLBGAA | |
| SCHEMBL30406832 | 0.81 | NR1H2 (0.38) | POLBGAA | |
| SCHEMBL23579120 | 0.78 | ALDH1A1 (0.48) | ALDH1A1POLBMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081199-A2 | LIPOXYGENASE INHIBITORS | SRI International (US) | 2022-11-02 | — | — | EP | disclosed |
| CN-115135316-A | Lipoxygenase inhibitors | 思研（SRI）国际顾问与咨询公司 | 2022-09-30 | — | — | CN | disclosed |
| WO-2021133689-A2 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2021-07-01 | — | — | WO | disclosed |
| WO-2021133689-A2 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2021-07-01 | — | — | WO | disclosed |