Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 5/20 | 0.76 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.67 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2319255 | 0.81 | EPHX2 (0.60) | CHRM1CHRM3CHRM2ALDH1A1HTT | |
| SCHEMBL29923548 | 0.80 | EPHX2 (0.71) | CHRM1KMT2ATDP1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2318668 | 0.80 | EPHX2 (0.58) | CHRM1CHRM3CHRM2ALDH1A1HTT | |
| SCHEMBL2320220 | 0.77 | CHRM1 (0.58) | CHRM1KMT2ATDP1 | |
| SCHEMBL1191122 | 0.77 | CHRM3 (0.62) | CHRM1CHRM3CHRM2ALDH1A1HTT | |
| SCHEMBL5067157 | 0.76 | KMT2A (0.61) | CHRM1ALDH1A1HTTNPSR1KMT2A | |
| SCHEMBL16438653 | 0.76 | CHRM3 (1.00) | CHRM1CHRM3CHRM2 | |
| SCHEMBL17796937 | 0.76 | CHRM3 (1.00) | CHRM1CHRM3CHRM2 | |
| SCHEMBL17796934 | 0.76 | CHRM3 (1.00) | CHRM1CHRM3CHRM2 | |
| SCHEMBL264806 | 0.76 | CHRM3 (1.00) | CHRM1CHRM3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2352730-A2 | BIOLOGICALLY ACTIVE AMIDES | H. Lundbeck A/S (DK) | 2011-08-10 | — | — | EP | disclosed |
| WO-2010053861-A2 | BIOLOGICALLY ACTIVE AMIDES | H. LUNDBECK A/S (DK) | 2010-05-14 | — | — | WO | disclosed |