Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5062079 | 0.80 | KDM4E (0.77) | KMT2AALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL5062917 | 0.77 | ALDH1A1 (0.53) | KMT2AALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL10502377 | 0.77 | KMT2A (1.00) | KMT2AALDH1A1KDM4EHSD17B10TSHR | |
| SCHEMBL10914678 | 0.77 | ALDH1A1 (0.72) | KMT2AALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL12415572 | 0.77 | KDM4E (0.53) | KMT2AALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL2358004 | 0.76 | CHRM1 (0.76) | KMT2AALDH1A1CHRM1NPSR1L3MBTL1 | |
| SCHEMBL31439556 | 0.76 | SMN1; SMN2 (0.54) | KMT2AALDH1A1KDM4EHSD17B10MAPK10 | |
| SCHEMBL5273515 | 0.76 | ALDH1A1 (0.51) | KMT2AALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL29923548 | 0.75 | EPHX2 (0.71) | KMT2ACHRM1TSHRTDP1SMN1; SMN2 | |
| SCHEMBL5067131 | 0.75 | ALDH1A1 (0.50) | KMT2AALDH1A1KDM4EHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221108-A1 | Anthranilic Acid Derivatives As Hm74A Receptor Agonists | SMITHKLINE BEECHAM CORPORATION | 2008-09-11 | — | — | US | disclosed |
| US-20080221108-A1 | Anthranilic Acid Derivatives As Hm74A Receptor Agonists | SMITHKLINE BEECHAM CORPORATION | 2008-09-11 | — | — | US | disclosed |
| EP-1848699-A1 | ANTHRANILIC ACID DERIVATIVES AS HM74A RECEPTOR AGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-10-31 | — | — | EP | disclosed |
| WO-2006085112-A1 | ANTHRANILIC ACID DERIVATIVES AS HM74A RECEPTOR AGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-08-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221108-A1 | Anthranilic Acid Derivatives As Hm74A Receptor Agonists | ANTXR2, GPR84, HCAR1 | KMT2A 1142/4885ALDH1A1 888/4885CHRM1 106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.