Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.52 |
| ▸ | ALK | Q9UM73 | 6/20 | 0.48 |
| ▸ | INSR | P06213 | 5/20 | 0.48 |
| ▸ | IGF1R | P08069 | 4/20 | 0.48 |
| ▸ | PKMYT1 | Q99640 | 2/20 | 0.47 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.43 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.43 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 3/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | MAP3K7 | O43318 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.43 |
| ▸ | CCNK | O75909 | 1/20 | 0.42 |
| ▸ | CCND3 | P30281 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28604830 | 0.81 | SLC2A1 (0.59) | SLC2A1ALKINSRIGF1RPKMYT1 | |
| SCHEMBL23581207 | 0.80 | JAK3 (0.61) | SLC2A1FGFR1JAK3MAP3K7MAPK1 | |
| SCHEMBL23581168 | 0.79 | SLC2A1 (0.52) | SLC2A1ALKINSRIGF1RPKMYT1 | |
| SCHEMBL25139769 | 0.78 | SLC2A1 (0.52) | SLC2A1ALKINSRIGF1RPKMYT1 | |
| SCHEMBL30044163 | 0.78 | SLC2A1 (0.52) | SLC2A1ALKINSRIGF1RPKMYT1 | |
| SCHEMBL23581166 | 0.76 | SLC2A1 (0.53) | SLC2A1ALKINSRIGF1RPKMYT1 | |
| SCHEMBL30045001 | 0.74 | SLC2A1 (0.54) | SLC2A1ALKPKMYT1FGFR1JAK3 | |
| SCHEMBL23606813 | 0.74 | SLC2A1 (0.54) | SLC2A1ALKPKMYT1FGFR1JAK3 | |
| SCHEMBL30044417 | 0.74 | ALK (0.60) | ALKINSRIGF1RPTK2FGFR1 | |
| SCHEMBL30045121 | 0.74 | ALK (0.56) | ALKINSRIGF1RFGFR1FGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021129561-A1 | CYANO-SUBSTITUTED PYRIDINE AND CYANO-SUBSTITUTED PYRIMIDINE COMPOUND AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 北京赛特明强医药科技有限公司 | 2021-07-01 | — | — | WO | disclosed |