Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.59 |
| ▸ | PKMYT1 | Q99640 | 2/20 | 0.55 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.54 |
| ▸ | ALK | Q9UM73 | 10/20 | 0.52 |
| ▸ | INSR | P06213 | 6/20 | 0.52 |
| ▸ | IGF1R | P08069 | 5/20 | 0.52 |
| ▸ | JAK3 | P52333 | 1/20 | 0.52 |
| ▸ | PLK1 | P53350 | 2/20 | 0.51 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.51 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.49 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.49 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.49 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23581168 | 0.90 | SLC2A1 (0.52) | SLC2A1PKMYT1MAP3K7ALKINSR | |
| SCHEMBL23581166 | 0.87 | SLC2A1 (0.53) | SLC2A1PKMYT1MAP3K7ALKINSR | |
| SCHEMBL23581207 | 0.86 | JAK3 (0.61) | SLC2A1MAP3K7JAK3FGFR1EGFR | |
| SCHEMBL25139769 | 0.85 | SLC2A1 (0.52) | SLC2A1PKMYT1MAP3K7ALKINSR | |
| SCHEMBL30044163 | 0.85 | SLC2A1 (0.52) | SLC2A1PKMYT1MAP3K7ALKINSR | |
| SCHEMBL23581174 | 0.81 | SLC2A1 (0.52) | SLC2A1PKMYT1MAP3K7ALKINSR | |
| SCHEMBL28953571 | 0.80 | ALK (0.58) | ALKINSRIGF1RPLK1PTK2 | |
| SCHEMBL28532459 | 0.80 | FGFR1 (0.49) | ALKIGF1RJAK3PLK1PTK2 | |
| SCHEMBL30379611 | 0.80 | FGFR1 (0.49) | ALKIGF1RJAK3PLK1PTK2 | |
| SCHEMBL25139831 | 0.80 | ALK (0.60) | MAP3K7ALKINSRIGF1RJAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113087671-B | Cyano-substituted pyridine and cyano-substituted pyrimidine compounds, and preparation methods and applications thereof | 北京赛特明强医药科技有限公司 | 2022-10-21 | — | — | CN | disclosed |
| CN-113087671-A | Cyano-substituted pyridine and cyano-substituted pyrimidine compounds, and preparation methods and applications thereof | 北京赛特明强医药科技有限公司 | 2021-07-09 | — | — | CN | disclosed |