SCHEMBL235835

SCHEMBL235835

CCCCCCCCCC=CC=CC=CC=CC=CC=CC(=O)O[C@H](COC(=O)CCCCCCCCCCCCCCC)COP(=O)(O)OC[C@H](N)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
P2RY10 O00398 8/20 0.66
GPR174 Q9BXC1 4/20 0.66
GPR34 Q9UPC5 4/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL234318 1.00 P2RY10 (0.66) P2RY10GPR174GPR34
SCHEMBL28206519 0.93 P2RY10 (0.56) P2RY10GPR174GPR34
SCHEMBL236702 0.93 P2RY10 (0.56) P2RY10GPR174GPR34
SCHEMBL3409912 0.93 P2RY10 (0.56) P2RY10GPR174GPR34
SCHEMBL3406657 0.92 P2RY10 (0.57) P2RY10GPR174GPR34
SCHEMBL25351937 0.88 SELP (0.56) P2RY10GPR174GPR34
SCHEMBL234324 0.88 SELP (0.56) P2RY10GPR174GPR34
SCHEMBL235809 0.88 SELP (0.56) P2RY10GPR174GPR34
SCHEMBL22532037 0.88 P2RY10 (0.78) P2RY10GPR174GPR34
SCHEMBL20481087 0.88 P2RY10 (0.78) P2RY10GPR174GPR34

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230302154-A1 NANODRUGS FOR TARGETED DRUG DELIVERY AND USE THEREOF UNIVERSITY OF CONNECTICUT 2023-09-28 US disclosed
EP-3357490-A1 FUSOGENIC PROPERTIES OF SAPOSIN C AND RELATED PROTEINS AND POLYPEPTIDES FOR APPLICATION TO TRANSMEMBRANE DRUG DELIVERY SYSTEMS Children's Hospital Medical Center (US) 2018-08-08 EP disclosed
US-10039715-B2 Liposomal formulation of nonglycosidic ceramides and uses thereof LUDWIG INSTITUTE FOR CANCER RESEARCH LTD. (US) 2018-08-07 US disclosed
EP-2654779-B1 LIPOSOMAL FORMULATION OF NONGLYCOSIDIC CERAMIDES AND USES THEREOF LUDWIG INST FOR CANCER RES LTD (US) 2018-02-28 EP disclosed
EP-2020988-B1 COMPOSITIONS COMPRISING FUSOGENIC PROTEINS OR POLYPEPTIDES DERIVED FROM PROSAPOSIN FOR APPLICATION IN TRANSMEMBRANE DRUG DELIVERY SYSTEMS CHILDREN'S HOSPITAL MEDICAL CENTER (US) 2017-08-16 EP disclosed
US-20170105936-A1 LIPOSOMAL FORMULATION OF NONGLYCOSIDIC CERAMIDES AND USES THEREOF LUDWIG INSTITUTE FOR CANCER RESEARCH LTD. (US) 2017-04-20 US disclosed
US-20160200784-A1 FUSOGENIC PROPERTIES OF SAPOSIN C AND RELATED PROTEINS AND PEPTIDES FOR APPLICATION TO TRANSMEMBRANE DRUG DELIVERY SYSTEMS CHILDREN'S HOSPITAL MEDICAL CENTER 2016-07-14 US disclosed
US-20140050780-A1 LIPOSOMAL FORMULATION OF NONGLYCOSIDIC CERAMIDES AND USES THEREOF LUDWIG INSTITUTE FOR CANCER RESEARCH LTD. (US) 2014-02-20 US disclosed
EP-2578237-A1 Compositions and methods for enhancing contrast in imaging Marval Biosciences, Inc. (US) 2013-04-10 EP disclosed
US-20120020878-A1 FUSOGENIC PROPERTIES OF SAPOSIN C AND RELATED PROTEINS AND PEPTIDES FOR APPLICATION TO TRANSMEMBRANE DRUG DELIVERY SYSTEMS CHILDREN'S HOSPITAL MEDICAL CENTER (US) 2012-01-26 US disclosed
US-20120003159-A1 COMPOSITIONS AND METHODS FOR ENHANCING CONTRAST IN IMAGING BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2012-01-05 US disclosed
US-7785568-B2 Sterically stabilized liposomes with hydrophilic polymers on surface; computed tomography MARVAL BIOSCIENCES, INC. (US) 2010-08-31 US disclosed
US-20080131369-A1 Sterically stabilized liposomes with hydrophilic polymers on surface; computed tomography MARVEL THERAPEUTICS (US) 2008-06-05 US disclosed
US-20070212303-A1 Sterically stabilized liposomes with hydrophilic polymers on surface; computed tomography MARVAL PHARMA, INC. 2007-09-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140050780-A1 LIPOSOMAL FORMULATION OF NONGLYCOSIDIC CERAMIDES AND USES THEREOF CERS2, CERT1, SGMS1 P2RY10 1820/4885GPR174 2764/4885GPR34 1880/4885
US-20170105936-A1 LIPOSOMAL FORMULATION OF NONGLYCOSIDIC CERAMIDES AND USES THEREOF CERS2, CERT1, SGMS1 P2RY10 1820/4885GPR174 2764/4885GPR34 1880/4885
US-10039715-B2 Liposomal formulation of nonglycosidic ceramides and uses thereof CERS2, CERT1, SGMS1 P2RY10 1820/4885GPR174 2764/4885GPR34 1880/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.