SCHEMBL236702

SCHEMBL236702

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nearest known ligand 0.60

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
P2RY10 O00398 10/20 0.56
GPR34 Q9UPC5 4/20 0.55
GPR174 Q9BXC1 4/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3409912 1.00 P2RY10 (0.56) P2RY10GPR34GPR174
SCHEMBL28206519 1.00 P2RY10 (0.56) P2RY10GPR34GPR174
SCHEMBL3406657 0.99 P2RY10 (0.57) P2RY10GPR34GPR174
SCHEMBL235835 0.93 P2RY10 (0.66) P2RY10GPR34GPR174
SCHEMBL234318 0.93 P2RY10 (0.66) P2RY10GPR34GPR174
SCHEMBL3409659 0.92 P2RY10 (0.60) P2RY10GPR34GPR174
SCHEMBL25252924 0.87 PLA2G2C (0.48) P2RY10GPR34
SCHEMBL235778 0.87 PLA2G2C (0.48) P2RY10GPR34
SCHEMBL1296680 0.86 PLA2G2C (0.49) P2RY10GPR34
SCHEMBL1296985 0.86 PLA2G2C (0.49) P2RY10GPR34

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240408032-A1 LIPID-BASED RNA FORMULATIONS SUITABLE FOR THERAPY BioNTech SE (DE) 2024-12-12 US claimed
EP-4398882-A1 LIPID-BASED RNA FORMULATIONS SUITABLE FOR THERAPY BioNTech SE (DE) 2024-07-17 EP claimed
WO-2023036960-A1 LIPID-BASED RNA FORMULATIONS SUITABLE FOR THERAPY BioNTech SE (DE) 2023-03-16 WO claimed
US-20240408032-A1 LIPID-BASED RNA FORMULATIONS SUITABLE FOR THERAPY BioNTech SE (DE) 2024-12-12 US disclosed
EP-4398882-A1 LIPID-BASED RNA FORMULATIONS SUITABLE FOR THERAPY BioNTech SE (DE) 2024-07-17 EP disclosed
CN-118265522-A Lipid-based RNA formulations suitable for treatment 生物技术欧洲股份公司 2024-06-28 CN disclosed
US-20230302154-A1 NANODRUGS FOR TARGETED DRUG DELIVERY AND USE THEREOF UNIVERSITY OF CONNECTICUT 2023-09-28 US disclosed
WO-2023036960-A1 LIPID-BASED RNA FORMULATIONS SUITABLE FOR THERAPY BioNTech SE (DE) 2023-03-16 WO disclosed
US-20220193108-A1 Immunotherapeutic Nanoparticles And Methods Relating Thereto WAKE FOREST UNIVERSITY HEALTH SCIENCES 2022-06-23 US disclosed
WO-2022040435-A1 NANODRUGS FOR TARGETED DRUG DELIVERY AND USE THEREOF THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2022-02-24 WO disclosed
WO-2020210317-A1 IMMUNOTHERAPEUTIC NANOPARTICLES AND METHODS RELATING THERETO WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) 2020-10-15 WO disclosed
WO-2010126319-A2 LIPOPEPTIDE WITH SPECIFIC AFFINITY TO THE FC REGION OF AN ANTIBODY, AND ANTIGEN-RECOGNIZING LIPID NANOPARTICLE COMPRISING SAME 고려대학교 산학협력단 (KR) 2010-11-04 WO disclosed
US-7785568-B2 Sterically stabilized liposomes with hydrophilic polymers on surface; computed tomography MARVAL BIOSCIENCES, INC. (US) 2010-08-31 US disclosed
WO-2010053489-A1 FUSOGENIC PROPERTIES OF SAPOSIN C AND RELATED PROTEINS AND PEPTIDES FOR APPLICATION TO TRANSMEMBRANE DRUG DELIVERY SYSTEMS CHILDREN'S HOSPITAL MEDICAL CENTER (US) 2010-05-14 WO disclosed
EP-2081552-A2 SPONTANEOUSLY FORMING ELLIPSOIDAL PHOSPHOLIPID UNILAMELLAR VESICLES Children's Hospital Medical Center (US) 2009-07-29 EP disclosed
EP-2020988-A2 COMPOSITIONS COMPRISING FUSOGENIC PROTEINS OR POLYPEPTIDES DERIVED FROM PROSAPOSIN FOR APPLICATION IN TRANSMEMBRANE DRUG DELIVERY SYSTEMS Children's Hospital Medical Center (US) 2009-02-11 EP disclosed
US-20080131369-A1 Sterically stabilized liposomes with hydrophilic polymers on surface; computed tomography MARVEL THERAPEUTICS (US) 2008-06-05 US disclosed
WO-2008051818-A2 SPONTANEOUSLY FORMING ELLIPSOIDAL PHOSPHOLIPID UNILAMELLAR VESICLES CHILDREN'S HOSPITAL MEDICAL CENTER (US) 2008-05-02 WO disclosed
WO-2007127439-A2 COMPOSITIONS COMPRISING FUSOGENIC PROTEINS OR POLYPEPTIDES DERIVED FROM PROSAPOSIN FOR APPLICATION IN TRANSMEMBRANE DRUG DELIVERY SYSTEMS CHILDREN'S HOSPITAL MEDICAL CENTER (US) 2007-11-08 WO disclosed
US-20070212303-A1 Sterically stabilized liposomes with hydrophilic polymers on surface; computed tomography MARVAL PHARMA, INC. 2007-09-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240408032-A1 LIPID-BASED RNA FORMULATIONS SUITABLE FOR THERAPY PHOSPHO1, PLIN3, SARNP P2RY10 4300/4885GPR34 4287/4885GPR174 3568/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.