Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | XIAP | P98170 | 6/20 | 0.35 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | ASAH1 | Q13510 | 5/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2358516 | 1.00 | TACR1 (0.36) | TACR1KMT2AHDAC6XIAPBIRC2 | |
| SCHEMBL4777094 | 0.78 | CA12 (0.34) | KMT2AHDAC6XIAPBIRC2ASAH1 | |
| SCHEMBL3852283 | 0.75 | ELANE (0.42) | XIAPELANE | |
| SCHEMBL2358520 | 0.75 | ELANE (0.42) | XIAPELANE | |
| SCHEMBL2209223 | 0.73 | TP53 (0.39) | HDAC6BIRC2ELANE | |
| SCHEMBL2212581 | 0.73 | ELANE (0.49) | ELANE | |
| SCHEMBL2212579 | 0.73 | ELANE (0.49) | ELANE | |
| SCHEMBL2209218 | 0.73 | TP53 (0.39) | HDAC6BIRC2ELANE | |
| SCHEMBL3832813 | 0.72 | CA12 (0.38) | KMT2AHDAC6BIRC2ELANE | |
| SCHEMBL3830340 | 0.70 | BIRC2 (0.37) | XIAPBIRC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989441-B2 | Organic compounds | NOVARTIS AG (CH) | 2011-08-02 | — | — | US | claimed |