⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17963377 | 0.79 | — | — | |
| SCHEMBL1628171 | 0.79 | — | — | |
| SCHEMBL6218499 | 0.78 | LMNA (0.37) | — | |
| SCHEMBL6502038 | 0.75 | — | — | |
| SCHEMBL27524799 | 0.75 | — | — | |
| SCHEMBL557653 | 0.75 | — | — | |
| SCHEMBL2038618 | 0.75 | KDM4E (0.39) | — | |
| SCHEMBL7629931 | 0.72 | KDM4E (0.35) | — | |
| SCHEMBL3342146 | 0.71 | — | — | |
| SCHEMBL4489846 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108218873-A | Inhibitors of influenza viruses replication and application thereof | 广东东阳光药业有限公司 | 2018-06-29 | — | — | CN | disclosed |
| EP-2349260-A1 | JANUS KINASE INHIBITORS FOR TREATMENT OF DRY EYE AND OTHER EYE RELATED DISEASES | Incyte Corporation (US) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010039939-A1 | JANUS KINASE INHIBITORS FOR TREATMENT OF DRY EYE AND OTHER EYE RELATED DISEASES | INCYTE CORPORATION (US) | 2010-04-08 | — | — | WO | disclosed |
| CN-1489577-A | Cyanothioacetamide derivatives and process for preparing same | �ձ�������ʽ���� | 2004-04-14 | — | — | CN | disclosed |