Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 13/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | TTR | P02766 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.63 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.63 |
| ▸ | PPARG | P37231 | 1/20 | 0.63 |
| ▸ | HTR2B | P41595 | 1/20 | 0.63 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.63 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.63 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.39 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29840626 | 0.83 | PPARA (0.63) | PPARASMN1; SMN2CYP2C9TDP1TTR | |
| SCHEMBL21753583 | 0.83 | PPARA (0.63) | PPARASMN1; SMN2CYP2C9TDP1TTR | |
| SCHEMBL21757422 | 0.81 | PPARA (0.43) | PPARASMN1; SMN2CYP2C9TDP1TTR | |
| SCHEMBL21753587 | 0.81 | PPARA (0.59) | PPARASMN1; SMN2CYP2C9TDP1TTR | |
| SCHEMBL21753575 | 0.79 | PPARA (0.64) | PPARASMN1; SMN2CYP2C9TDP1TTR | |
| SCHEMBL21753577 | 0.78 | PPARA (0.56) | PPARASMN1; SMN2CYP2C9TDP1TTR | |
| SCHEMBL21753568 | 0.78 | PPARA (0.52) | PPARASMN1; SMN2CYP2C9TDP1TTR | |
| SCHEMBL11090319 | 0.77 | PPARA (0.75) | PPARASMN1; SMN2CYP2C9TDP1TTR | |
| Gemfibrozil SCHEMBL20770039 | 0.77 | PPARA (1.00) | PPARASMN1; SMN2CYP2C9TDP1TTR | |
| Gemfibrozil SCHEMBL4813 | 0.77 | PPARA (1.00) | PPARASMN1; SMN2CYP2C9TDP1TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3842410-A1 | FIBRIC ACID COMPOUND AND MEDICAL USE THEREOF | Beijing Wholesomeyird Sci & Tech Co., Ltd. (CN) | 2021-06-30 | — | — | EP | disclosed |