Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4099428 | 0.90 | ADRA1A (0.48) | ADRA1APRMT1PLA2G4AATMPLA2G2A | |
| SCHEMBL4092950 | 0.85 | ADRA1A (0.57) | ADRA1APRMT1PLA2G4APLA2G2AEPHX2 | |
| SCHEMBL4094844 | 0.83 | ADRA1A (0.60) | ADRA1APRMT1PLA2G4APLA2G2AEPHX2 | |
| SCHEMBL17234293 | 0.79 | PRMT1 (0.44) | ADRA1APRMT1PLA2G4AATMEPHX2 | |
| SCHEMBL3194539 | 0.78 | ECE1 (0.43) | ADRA1APRMT1PLA2G2ALMNATSHR | |
| SCHEMBL13227081 | 0.76 | EPHX1 (0.39) | MEN1KMT2ATSHR | |
| SCHEMBL8215024 | 0.75 | PRMT1 (0.47) | ADRA1APRMT1PLA2G4AATMEPHX2 | |
| SCHEMBL20799751 | 0.75 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL14868287 | 0.75 | EPHX1 (0.43) | TSHR | |
| SCHEMBL5125268 | 0.74 | PRMT1 (0.61) | ADRA1APRMT1PLA2G4AEPHX2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3950673-A1 | INHIBITORS OF CREATINE TRANSPORT AND USES THEREOF | Inspirna, Inc. (US) | 2022-02-09 | — | — | EP | disclosed |
| EP-3137447-B1 | INHIBITORS OF CREATINE TRANSPORT AND USES THEREOF | RGENIX INC (US) | 2021-06-30 | — | — | EP | disclosed |