SCHEMBL23587151

SCHEMBL23587151

Cc1nccc2c1ccc1ccc(F)cc12

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCNB2 O95067 1/20 0.51
CDK1 P06493 1/20 0.51
CCNB1 P14635 1/20 0.51
CCNA2 P20248 1/20 0.51
CDK2 P24941 1/20 0.51
CCNA1 P78396 1/20 0.51
CDK5 Q00535 1/20 0.51
CDK5R1 Q15078 1/20 0.51
CCNB3 Q8WWL7 1/20 0.51
CYP2A6 P11509 1/20 0.44
TDO2 P48775 1/20 0.41
HASPIN Q8TF76 1/20 0.41
TYMS P04818 1/20 0.39
CYP19A1 P11511 1/20 0.38
TRPA1 O75762 4/20 0.38
CASP3 P42574 1/20 0.36
CYP3A4 P08684 2/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
APEX1 P27695 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17861316 0.87 CYP2A6 (0.53) CCNB2CDK1CCNB1CCNA2CDK2
SCHEMBL2757276 0.79 CYP2A6 (0.53) CCNB2CDK1CCNB1CCNA2CDK2
SCHEMBL21870525 0.79 MAPT (0.61) CCNB2CDK1CCNB1CCNA2CDK2
SCHEMBL26696146 0.79 CDK2 (0.37) CCNB2CDK1CCNB1CCNA2CDK2
SCHEMBL12405289 0.78 CYP1A2 (0.48) CYP2A6TYMSLMNAMAPTKIF11
SCHEMBL21864506 0.78 CCNB2 (0.38) CCNB2CDK1CCNB1CCNA2CDK2
SCHEMBL26873305 0.76 CYP2A6 (0.70) CYP2A6TDO2CYP3A4LMNAMAPT
SCHEMBL14341059 0.76 CYP2A6 (0.70) CYP2A6TDO2CYP3A4LMNAMAPT
SCHEMBL26873052 0.75 CYP2A6 (0.53) CCNB2CDK1CCNB1CCNA2CDK2
SCHEMBL12266516 0.73 CYP2A6 (0.56) CCNB2CDK1CCNB1CCNA2CDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3842444-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE Samsung Electronics Co., Ltd. (KR) 2021-06-30 EP disclosed