SCHEMBL21870525

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL22462704	0.89	MAPT (0.61)	MAPTMAPK1LMNACYP3A4APEX1
	SCHEMBL23557300	0.89	MAPT (0.61)	MAPTMAPK1LMNACYP3A4APEX1
	SCHEMBL1315422	0.87	MAPT (0.47)	MAPTMAPK1LMNACYP3A4APEX1
	SCHEMBL241172	0.79	CYP3A4 (0.43)	MAPTMAPK1LMNACYP3A4APEX1
	SCHEMBL30738146	0.79	CYP3A4 (0.43)	MAPTMAPK1LMNACYP3A4APEX1
	SCHEMBL22167065	0.79	MAPT (0.47)	MAPTMAPK1LMNACYP3A4APEX1
	SCHEMBL26696146	0.79	CDK2 (0.37)	MAPTMAPK1LMNACYP3A4APEX1
	SCHEMBL23587151	0.79	CCNB2 (0.51)	MAPTMAPK1LMNACYP3A4APEX1
	SCHEMBL21870514	0.78	LMNA (0.56)	MAPTMAPK1LMNACYP3A4APEX1
	SCHEMBL12405289	0.78	CYP1A2 (0.48)	MAPTLMNAALDH1A1TYMSCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.