SCHEMBL23587290

SCHEMBL23587290

CC1=CC(c2c(O)c(C3C=C(C)CCC3)c(O)c(C3C=C(C)CCC3)c2O)CCC1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 2/20 0.33
HKDC1 Q2TB90 1/20 0.32
CNR2 P34972 3/20 0.32
OPRM1 P35372 1/20 0.30
GPR55 Q9Y2T6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22537449 0.81 CNR1 (0.49) CNR1CNR2OPRM1GPR55
SCHEMBL22705363 0.81 GPR55 (0.46) CNR1CNR2OPRM1GPR55
SCHEMBL31545325 0.81 GPR55 (0.46) CNR1CNR2OPRM1GPR55
SCHEMBL18386358 0.81 CNR1 (0.49) CNR1CNR2OPRM1GPR55
SCHEMBL24525885 0.78 CNR1 (0.37) CNR1CNR2OPRM1GPR55
SCHEMBL23587174 0.78 CNR1 (0.33) CNR1CNR2OPRM1GPR55
SCHEMBL18386376 0.77 GPR55 (0.35) CNR1CNR2OPRM1GPR55
SCHEMBL23948549 0.77 GPR55 (0.52) CNR1CNR2OPRM1GPR55
SCHEMBL22430730 0.77 GPR55 (0.52) CNR1CNR2OPRM1GPR55
SCHEMBL23643035 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3262021-B1 TREATMENT METHOD, COMPOUNDS, AND METHOD OF INCREASING TRPV2 ACTIVITY FEINSTEIN INST MEDICAL RES (US) 2021-06-30 EP disclosed