SCHEMBL2358765

SCHEMBL2358765

C=CCN(O)C(CS)C(=O)O

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
PTGS1 P23219 1/20 0.32
SLC7A11 Q9UPY5 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2358767 1.00 ALDH1A1 (0.32) ALDH1A1PTGS1SLC7A11
SCHEMBL4541471 0.82 ALDH1A1 (0.33) ALDH1A1PTGS1SLC7A11
SCHEMBL4541470 0.82 ALDH1A1 (0.33) ALDH1A1PTGS1SLC7A11
SCHEMBL3664276 0.80 ALDH1A1 (0.32) ALDH1A1PTGS1SLC7A11
SCHEMBL1158205 0.80 ALDH1A1 (0.32) ALDH1A1PTGS1SLC7A11
SCHEMBL4409628 0.80 ALDH1A1 (0.32) ALDH1A1PTGS1SLC7A11
SCHEMBL11499006 0.80 TDP1 (0.34) ALDH1A1
SCHEMBL1023965 0.78 ALDH1A1 (0.31) ALDH1A1PTGS1SLC7A11
SCHEMBL8752967 0.78 ALDH1A1 (0.31) ALDH1A1PTGS1SLC7A11
SCHEMBL11564544 0.78 PTGS1 (0.35) ALDH1A1PTGS1SLC7A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0346883-B1 Expectorant comprising hydroxy-alkylcysteine derivative SS PHARMACEUTICAL CO (JP) 1994-05-18 EP claimed
EP-0346882-B1 HYDROXYALKYLCYSTEINE DERIVATIVE AND EXPECTORANT CONTAINING THE SAME SS PHARMACEUTICAL CO., LTD. (JP) 1993-09-29 EP claimed
US-5047428-A Side effect reduction SS PHARMACEUTICAL CO., LTD. (JP) 1991-09-10 US claimed
US-4906665-A Hydroxyalkylcysteine derivative and expectorant containing the same SS PHARMACEUTICAL CO., LTD. (JP) 1990-03-06 US claimed
EP-0346883-A2 Expectorant comprising hydroxy-alkylcysteine derivative SS PHARMACEUTICAL CO., LTD. (JP) 1989-12-20 EP claimed
EP-0346882-A2 Hydroxyalkylcysteine derivative and expectorant containing the same SS PHARMACEUTICAL CO., LTD. (JP) 1989-12-20 EP claimed
JP-2003674-A None JP disclosed
EP-1391202-B1 LIQUID DRUG PREPARATIONS HISAMITSU PHARMACEUTICAL CO (JP) 2011-08-03 EP disclosed
JP-2005126352-A DIARRHEA REMEDY MITSUBISHI PHARMA CORP 2005-05-19 JP disclosed
EP-0998926-B1 Oral preparation comprising S-(3-hydroxypropyl)-L-cysteine SSP CO LTD (JP) 2003-04-02 EP disclosed
EP-0346883-B1 Expectorant comprising hydroxy-alkylcysteine derivative SS PHARMACEUTICAL CO (JP) 1994-05-18 EP disclosed
EP-0346883-B1 Expectorant comprising hydroxy-alkylcysteine derivative SS PHARMACEUTICAL CO (JP) 1994-05-18 EP disclosed
EP-0346882-B1 HYDROXYALKYLCYSTEINE DERIVATIVE AND EXPECTORANT CONTAINING THE SAME SS PHARMACEUTICAL CO., LTD. (JP) 1993-09-29 EP disclosed
JP-H023674-A HYDROXYALKYLCYSTEINE DERIVATIVE AND EXPECTORANT CONTAINING THE SAME DERIVATIVE SS PHARMACEUT CO LTD 1990-01-09 JP disclosed
EP-0346883-A2 Expectorant comprising hydroxy-alkylcysteine derivative SS PHARMACEUTICAL CO., LTD. (JP) 1989-12-20 EP disclosed
EP-0346883-A2 Expectorant comprising hydroxy-alkylcysteine derivative SS PHARMACEUTICAL CO., LTD. (JP) 1989-12-20 EP disclosed
EP-0346882-A2 Hydroxyalkylcysteine derivative and expectorant containing the same SS PHARMACEUTICAL CO., LTD. (JP) 1989-12-20 EP disclosed
EP-0346882-A2 Hydroxyalkylcysteine derivative and expectorant containing the same SS PHARMACEUTICAL CO., LTD. (JP) 1989-12-20 EP disclosed
EP-0346882-A2 Hydroxyalkylcysteine derivative and expectorant containing the same SS PHARMACEUTICAL CO., LTD. (JP) 1989-12-20 EP disclosed
EP-0346883-A2 Expectorant comprising hydroxy-alkylcysteine derivative SS PHARMACEUTICAL CO., LTD. (JP) 1989-12-20 EP disclosed