Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 9/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.62 |
| ▸ | LYN | P07948 | 3/20 | 0.62 |
| ▸ | SYK | P43405 | 3/20 | 0.62 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.62 |
| ▸ | TXK | P42681 | 2/20 | 0.62 |
| ▸ | PLK4 | O00444 | 2/20 | 0.62 |
| ▸ | AURKA | O14965 | 2/20 | 0.62 |
| ▸ | JAK2 | O60674 | 2/20 | 0.62 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.62 |
| ▸ | LCK | P06239 | 2/20 | 0.62 |
| ▸ | FYN | P06241 | 2/20 | 0.62 |
| ▸ | CSF1R | P07333 | 2/20 | 0.62 |
| ▸ | RET | P07949 | 2/20 | 0.62 |
| ▸ | ROS1 | P08922 | 2/20 | 0.62 |
| ▸ | KIT | P10721 | 2/20 | 0.62 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23587676 | 0.86 | KDR (0.66) | KDRCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9277964 | 0.82 | BTK (0.59) | KDRCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL19913009 | 0.80 | KDR (0.68) | KDRCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL4816559 | 0.80 | KDR (0.62) | KDRCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL4976793 | 0.79 | KDR (0.51) | KDRCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL23587679 | 0.79 | BTK (0.58) | KDRCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL24576660 | 0.78 | KDR (0.64) | KDRCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL14419332 | 0.78 | KDR (0.77) | KDRCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL15997518 | 0.78 | KDR (0.77) | KDRCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL589388 | 0.78 | KDR (0.66) | KDRCYP3A4CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021133742-A1 | STABILIZATION OF MHC COMPLEXES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-07-01 | — | — | WO | disclosed |