Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.38 |
| ▸ | PTGES | O14684 | 6/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13027962 | 0.87 | MEN1 (0.68) | MEN1PABPC1KMT2ANPC1CA12 | |
| SCHEMBL891953 | 0.86 | MEN1 (0.51) | MEN1PABPC1KMT2ANPC1CA12 | |
| SCHEMBL891935 | 0.85 | MEN1 (0.50) | MEN1PABPC1KMT2ANPC1CA12 | |
| SCHEMBL22847416 | 0.85 | MEN1 (0.47) | MEN1PABPC1KMT2ANPC1CA12 | |
| SCHEMBL10644355 | 0.83 | MEN1 (0.51) | MEN1PABPC1KMT2ANPC1CA12 | |
| SCHEMBL25436251 | 0.82 | MEN1 (0.48) | MEN1PABPC1KMT2ANPC1CA12 | |
| SCHEMBL892211 | 0.82 | MEN1 (0.47) | MEN1PABPC1KMT2ANPC1CA12 | |
| SCHEMBL892401 | 0.81 | MEN1 (0.77) | MEN1PABPC1KMT2ANPC1CA12 | |
| Hydrochloric Acid SCHEMBL1335355 | 0.80 | MEN1 (0.75) | MEN1PABPC1KMT2ANPC1CA12 | |
| SCHEMBL31451983 | 0.77 | KMT2A (0.45) | MEN1PABPC1KMT2ANPC1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210198265-A1 | TEMOZOLOMIDE COMPOUNDS, POLYMERS PREPARED THEREFROM, AND METHOD OF TREATING A DISEASE | UNIVERSITY OF MASSACHUSETTS | 2021-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210198265-A1 | TEMOZOLOMIDE COMPOUNDS, POLYMERS PREPARED THEREFROM, AND METHOD OF TREATING A DISEASE | PBRM1, MGMT, TOP1 | MEN1 5/4885PABPC1 1794/4885KMT2A 401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.