Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 6/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10643552 | 0.89 | MEN1 (0.48) | MEN1PABPC1KMT2ACA12CA1 | |
| Mitozolomide SCHEMBL97695 | 0.88 | MEN1 (0.64) | MEN1PABPC1KMT2ACA12CA1 | |
| SCHEMBL3336603 | 0.84 | MEN1 (0.47) | MEN1PABPC1KMT2ACA12CA1 | |
| SCHEMBL3336299 | 0.84 | MEN1 (0.47) | MEN1PABPC1KMT2ACA12CA1 | |
| Water SCHEMBL10648619 | 0.83 | MEN1 (0.46) | MEN1PABPC1KMT2ACA12CA1 | |
| SCHEMBL23588609 | 0.83 | MEN1 (0.54) | MEN1PABPC1KMT2ACA12CA1 | |
| SCHEMBL10648478 | 0.81 | MEN1 (0.44) | MEN1PABPC1KMT2ACA12CA1 | |
| SCHEMBL3337129 | 0.81 | MEN1 (0.63) | MEN1PABPC1KMT2ACA12CA1 | |
| SCHEMBL891953 | 0.81 | MEN1 (0.51) | MEN1PABPC1KMT2ACA12CA1 | |
| SCHEMBL10646126 | 0.80 | CA12 (0.48) | MEN1PABPC1KMT2ACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252682-A2 | Tetrazines | MAY & BAKER LIMITED (GB) | 1988-01-13 | — | — | EP | disclosed |