⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL815455 | 0.54 | — | — | |
| SCHEMBL222064 | 0.50 | — | — | |
| SCHEMBL5229280 | 0.50 | — | — | |
| SCHEMBL1574564 | 0.50 | — | — | |
| SCHEMBL3083556 | 0.50 | — | — | |
| SCHEMBL447969 | 0.50 | — | — | |
| SCHEMBL2554291 | 0.44 | — | — | |
| SCHEMBL15510742 | 0.42 | — | — | |
| SCHEMBL6998282 | 0.42 | — | — | |
| SCHEMBL735951 | 0.41 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 456 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240217968-A1 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2024-07-04 | — | — | US | claimed |
| WO-2024115465-A1 | PHARMACEUTICAL COMPOUNDS AS PARP7 AND/OR PARP1 INHIBITORS | Duke Street Bio Limited (GB) | 2024-06-06 | — | — | WO | claimed |
| EP-4313300-A1 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2024-02-07 | — | — | EP | claimed |
| CN-117460723-A | Pharmaceutical compounds | 杜克街生物有限公司 | 2024-01-26 | — | — | CN | claimed |
| CN-111943890-B | Pharmaceutical compounds | 艾欧米制药有限公司 | 2023-10-31 | — | — | CN | claimed |
| WO-2023156386-A2 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2023-08-24 | — | — | WO | claimed |
| US-11130738-B2 | Pharmaceutical compound | IOMET PHARMA LTD. (GB) | 2021-09-28 | — | — | US | claimed |
| CN-107108556-B | Pharmaceutical compounds | 艾欧米制药有限公司 | 2020-09-29 | — | — | CN | claimed |
| US-20200172492-A1 | PHARMACEUTICAL COMPOUND | IOMET PHARMA LTD. (GB) | 2020-06-04 | — | — | US | claimed |
| US-10590086-B2 | Pharmaceutical compound | IOMET PHARMA LTD. (GB) | 2020-03-17 | — | — | US | claimed |
| US-20180354908-A1 | PHARMACEUTICAL COMPOUND | IOMET PHARMA LTD. (GB) | 2018-12-13 | — | — | US | claimed |
| EP-3215156-A2 | PHARMACEUTICAL COMPOUND | Iomet Pharma Ltd. (GB) | 2017-09-13 | — | — | EP | claimed |
| EP-3215155-A1 | INHIBITORS OF TRYPTOPHAN-2,3-DIOXYGENASE OR INDOLEAMINE-2,3-DIOXYGENASE | Iomet Pharma Ltd. (GB) | 2017-09-13 | — | — | EP | claimed |
| EP-3182972-A1 | PHARMACEUTICAL COMPOUND | Iomet Pharma Ltd. (GB) | 2017-06-28 | — | — | EP | claimed |
| US-20170107178-A1 | INDOLE DERIVATIVES FOR USE IN MEDICINE | IOMET PHARMA LTD. (GB) | 2017-04-20 | — | — | US | claimed |
| EP-3125883-A1 | INDOLE DERIVATIVES FOR USE IN MEDICINE | Iomet Pharma Ltd. (GB) | 2017-02-08 | — | — | EP | claimed |
| WO-2016071293-A2 | PHARMACEUTICAL COMPOUND | IOMET PHARMA LTD (GB) | 2016-05-12 | — | — | WO | claimed |
| WO-2016071283-A1 | INHIBITORS OF TRYPTOPHAN-2,3-DIOXYGENASE OR INDOLEAMINE-2,3-DIOXYGENASE | IOMET PHARMA LTD (GB) | 2016-05-12 | — | — | WO | claimed |
| WO-2016026772-A1 | PHARMACEUTICAL COMPOUND | IOMET PHARMA LTD (GB) | 2016-02-25 | — | — | WO | claimed |
| WO-2015150097-A1 | INDOLE DERIVATIVES FOR USE IN MEDICINE | IOMET PHARMA LTD (GB) | 2015-10-08 | — | — | WO | claimed |