SCHEMBL447969

SCHEMBL447969

C1=COCN=N1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3545604 0.55
SCHEMBL234918 0.50
SCHEMBL3083556 0.50
SCHEMBL235892 0.50
Hydrochloric Acid SCHEMBL23295202 0.47
SCHEMBL1449370 0.47
SCHEMBL1434293 0.45
SCHEMBL2554291 0.44
SCHEMBL1190870 0.38
SCHEMBL56190 0.38

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 648 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119101713-A Method for preparing 1,3, 4-oxadiazine compounds by oxidase catalysis 内蒙古民族大学 2024-12-10 CN claimed
CN-114828628-A Diamide suspension concentrate compositions FMC公司 2022-07-29 CN claimed
EP-1542692-B1 AMINOPYRIMIDINE DERIVATIVES FOR USE AS VANILLOID RECEPTOR LIGANDS FOR THE TREATMENT OF PAIN AMGEN INC (US) 2011-01-05 EP claimed
EP-2270006-A1 Pyridazine derivatives useful as vanilloid receptor ligands Amgen, Inc (US) 2011-01-05 EP claimed
EP-2099439-A2 METHODS FOR TREATING INFLAMMATORY DISEASE BY ADMINISTERING ALDEHYDES AND DERIVATIVES THEREOF ALFAMA - INVESTIGAÇÃO E DESENVOLVIMENTO DE PRODUTO (PT) 2009-09-16 EP claimed
US-7524874-B2 Vanilloid receptor ligands and their use in treatments AMGEN INC. (US) 2009-04-28 US claimed
US-7439360-B2 Vanilloid receptor ligands and their use in treatments AMGEN INC. (US) 2008-10-21 US claimed
US-7396831-B2 Vanilloid receptor ligands and their use in treatments AMGEN INC. (US) 2008-07-08 US claimed
US-7390907-B2 Vanilloid receptor ligands and their use in treatments AMGEN INC. (US) 2008-06-24 US claimed
WO-2008069688-A2 METHODS FOR TREATING INFLAMMATORY DISEASE BY ADMINISTERING ALDEHYDES AND DERIVATIVES THEREOF ALFAMA - INVESTIGAÇÃO E DESENVOLVIMENTO DE PRODUTOS FARMACÊUTICOS LDA (PT) 2008-06-12 WO claimed
CN-1450997-A Inhibitors of copper-containing amine oxidases BIOTIE THERAPIES CORP (FI) 2003-10-22 CN claimed
US-20030195201-A1 Vanilloid receptor ligands and their use in treatments AMGEN INC. 2003-10-16 US claimed
WO-2003049702-A2 VANILLOID RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS AMGEN INC. (US) 2003-06-19 WO claimed
EP-1301495-A2 INHIBITORS OF COPPER-CONTAINING AMINE OXIDASES Biotie Therapies Corp. (FI) 2003-04-16 EP claimed
EP-0891341-B1 1,3,4-OXADIAZINE DERIVATIVES AND THEIR USE AS PESTICIDES BAYER AG (DE) 2003-01-02 EP claimed
US-6342599-B1 REACTING SPECIFIED OXADIAZINE DERIVATIVES WITH ALKYLATING OR ACYLATING AGENTS, OR ALDEHYDES OR KETONES, OR THIONYLATING REAGENTS, IN PRESENCE OF DILUENT AND REACTION AUXILIARY IF REQUIRED BAYER AKTIENGESELLSCHAFT (DE) 2002-01-29 US claimed
WO-2002002541-A2 INHIBITORS OF COPPER-CONTAINING AMINE OXIDASES BIOTIE THERAPIES CORP. (FI) 2002-01-10 WO claimed
CN-1073090-C 1,3,4-oxadiazine derivatives and their use as pesticides BAYER AG (DE) 2001-10-17 CN claimed
US-6127364-A ANTHELMINTHICS, INSECTICIDES, ACARICIDES, AND NEMATICIDES. BAYER AKTIENGESELLSCHAFT (DE) 2000-10-03 US claimed
CN-1214683-A 1,3, 4-oxadiazine derivatives and their use as pesticides BAYER AG (DE) 1999-04-21 CN claimed