Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24802416 | 0.77 | — | — | |
| SCHEMBL27277801 | 0.77 | CYP3A4 (0.46) | — | |
| SCHEMBL13199244 | 0.77 | ATM (0.45) | GABRA1GABRB2CA2 | |
| SCHEMBL15957669 | 0.73 | AR (0.36) | — | |
| SCHEMBL25078242 | 0.72 | KRAS (0.33) | CA2 | |
| SCHEMBL25078522 | 0.72 | SOS1 (0.36) | GABRA1 | |
| SCHEMBL30949232 | 0.72 | SOS1 (0.36) | GABRA1 | |
| SCHEMBL28929735 | 0.72 | SOS1 (0.36) | GABRA1 | |
| Hydrochloric Acid SCHEMBL29723387 | 0.71 | ALDH1A1 (0.38) | GABRA1 | |
| SCHEMBL28655670 | 0.70 | SOS1 (0.36) | GABRA1GABRB2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130731-A1 | SUBSTITUTED TRICYCLIC COMPOUNDS | LUPIN LIMITED (IN) | 2021-07-01 | — | — | WO | disclosed |