Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 16/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23572602 | 1.00 | IDO1 (0.51) | IDO1MAPTSORT1 | |
| SCHEMBL23593347 | 1.00 | IDO1 (0.51) | IDO1MAPTSORT1 | |
| SCHEMBL26783183 | 0.81 | IDO1 (0.44) | IDO1MAPTSORT1 | |
| SCHEMBL26782969 | 0.80 | IDO1 (0.43) | IDO1MAPTSORT1 | |
| SCHEMBL21504228 | 0.76 | IDO1 (0.63) | IDO1MAPT | |
| SCHEMBL23572599 | 0.76 | IDO1 (0.54) | IDO1 | |
| SCHEMBL21504168 | 0.72 | IDO1 (0.58) | IDO1MAPT | |
| Hydrochloric Acid SCHEMBL21496291 | 0.71 | IDO1 (0.57) | IDO1MAPT | |
| SCHEMBL21504255 | 0.70 | IDO1 (0.81) | IDO1 | |
| SCHEMBL23593349 | 0.70 | MAPT (0.41) | IDO1MAPTSORT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11352320-B2 | Substituted [1.1.1] bicyclo compounds as indoleamine 2,3-dioxygenase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2022-06-07 | — | — | US | disclosed |
| US-20210198190-A1 | NOVEL SUBSTITUTED [1.1.1] BICYCLO COMPOUNDS AS INDOLEAMINE 2,3-DIOXYGENASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2021-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210198190-A1 | NOVEL SUBSTITUTED [1.1.1] BICYCLO COMPOUNDS AS INDOLEAMINE 2,3-DIOXYGENASE INHIBITORS | IDO1, IDO2, TPH1 | IDO1 1/4885MAPT 1889/4885SORT1 4649/4885 |
| US-11352320-B2 | Substituted [1.1.1] bicyclo compounds as indoleamine 2,3-dioxygenase inhibitors | IDO1, IDO2, TPH1 | IDO1 1/4885MAPT 1778/4885SORT1 4736/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.