Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2324654 | 0.79 | KDM1A (0.52) | HTR2CHTR2BCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL2360387 | 0.79 | KDM1A (0.52) | HTR2AHTR2CHTR2BSLC6A2SLC6A4 | |
| SCHEMBL9544430 | 0.79 | HTR2A (0.44) | FFAR1HTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL2321920 | 0.79 | KDM1A (0.56) | HTR2CSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3198056 | 0.78 | MAOB (0.48) | HTR2AHTR2CHTR2BCYP1A2CYP3A4 | |
| SCHEMBL2321966 | 0.78 | MAOB (0.48) | HTR2AHTR2CHTR2BCYP1A2CYP3A4 | |
| SCHEMBL4262044 | 0.78 | MAOB (0.48) | HTR2AHTR2CHTR2BCYP1A2CYP3A4 | |
| SCHEMBL2326665 | 0.74 | SLC6A2 (0.42) | HTR2AHTR2CHTR2BSLC6A2SLC6A4 | |
| SCHEMBL10527956 | 0.71 | FFAR1 (0.41) | FFAR1HTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL10527962 | 0.71 | FFAR1 (0.41) | FFAR1HTR2AHTR2CHTR2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | disclosed |