Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 5/20 | 0.36 |
| ▸ | RARA | P10276 | 2/20 | 0.36 |
| ▸ | RARG | P13631 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | PTPRO | Q16827 | 1/20 | 0.33 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14846051 | 0.92 | TSHR (0.48) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL20005274 | 0.90 | TSHR (0.43) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL14773018 | 0.89 | TSHR (0.46) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL15980421 | 0.89 | TSHR (0.46) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL14365592 | 0.89 | TSHR (0.46) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL15980423 | 0.89 | HSD17B10 (0.52) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL8755306 | 0.89 | TSHR (0.42) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL8755679 | 0.88 | RARB (0.41) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL7081007 | 0.88 | HSD17B10 (0.38) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL8979017 | 0.87 | FFAR1 (0.43) | TSHRHSD17B10FFAR1KCNH2PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127949-A1 | LIQUID CRYSTAL COMPOSITION ADAPTABLE TO RELATIVELY WIDE OPERATING TEMPERATURES AND USE THEREOF IN DEVICE | 北京八亿时空液晶科技股份有限公司 | 2021-07-01 | — | — | WO | disclosed |