Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20797832 | 0.80 | CHRM2 (0.55) | MAPTFUCA1CHRM2CHRM4CHRM5 | |
| SCHEMBL20811168 | 0.80 | CHRM2 (0.55) | MAPTFUCA1CHRM2CHRM4CHRM5 | |
| SCHEMBL5745796 | 0.76 | MAPT (0.47) | MAPTFUCA1CHRM2CHRM4CHRM5 | |
| SCHEMBL20046302 | 0.75 | MAPT (0.47) | MAPTFUCA1CHRM2CHRM4CHRM5 | |
| SCHEMBL6204675 | 0.75 | MAPT (0.47) | MAPTFUCA1CHRM2CHRM4CHRM5 | |
| SCHEMBL27969697 | 0.75 | MAPT (0.51) | MAPTFUCA1CHRM2CHRM4CHRM5 | |
| SCHEMBL20046647 | 0.75 | MAPT (0.47) | MAPTFUCA1CHRM2CHRM4CHRM5 | |
| SCHEMBL28192033 | 0.74 | CHRM2 (0.49) | MAPTFUCA1CHRM2CHRM4CHRM5 | |
| SCHEMBL27451598 | 0.74 | CHRM2 (0.49) | MAPTFUCA1CHRM2CHRM4CHRM5 | |
| SCHEMBL7301476 | 0.74 | CHRM2 (0.49) | MAPTFUCA1CHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021133750-A1 | SUBSTITUTED BICYCLIC PIPERIDINE DERIVATIVES USEFUL AS T CELL ACTIVATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-07-01 | — | — | WO | disclosed |