Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 5/20 | 0.40 |
| ▸ | DGKZ | Q13574 | 8/20 | 0.38 |
| ▸ | DGKA | P23743 | 2/20 | 0.38 |
| ▸ | ACACB | O00763 | 4/20 | 0.37 |
| ▸ | SCD | O00767 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23600283 | 0.88 | DGKZ (0.51) | DGKZDGKA | |
| SCHEMBL23564413 | 0.85 | DGKZ (0.39) | DGKZDGKA | |
| SCHEMBL23526928 | 0.85 | DGKZ (0.39) | DGKZDGKA | |
| SCHEMBL30900944 | 0.85 | DGKZ (0.39) | DGKZDGKA | |
| SCHEMBL23527170 | 0.80 | DGKZ (0.45) | DGKZDGKA | |
| SCHEMBL23526848 | 0.77 | DGKZ (0.49) | DGKZDGKA | |
| SCHEMBL23526997 | 0.77 | DGKZ (0.49) | DGKZDGKA | |
| SCHEMBL23600178 | 0.77 | DGKZ (0.49) | DGKZDGKA | |
| SCHEMBL23527091 | 0.77 | DGKZ (0.49) | DGKZDGKA | |
| SCHEMBL23526924 | 0.77 | DGKZ (0.49) | DGKZDGKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021133750-A1 | SUBSTITUTED BICYCLIC PIPERIDINE DERIVATIVES USEFUL AS T CELL ACTIVATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-07-01 | — | — | WO | disclosed |